HCSGD entry for KLK2

1. General information

Official gene symbolKLK2
Entrez ID3817
Gene full namekallikrein-related peptidase 2
Other gene symbolsKLK2A2 hGK-1 hK2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004252Serine-type endopeptidase activityIDA IEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0022617Extracellular matrix disassemblyTASbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54700586980.93621878350.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0280391262
GSE13712_SHEARUp0.0218733895
GSE13712_STATICUp0.1286282462
GSE19018Up0.0869157646
GSE19899_A1Up0.1276431548
GSE19899_A2Up0.0426117983
PubMed_21979375_A1Down-0.1309090163
PubMed_21979375_A2Down-0.0115851462
GSE35957Up0.1323868204
GSE36640Up0.1133688925
GSE54402Up0.0181643977
GSE9593Down-0.0343700275
GSE43922Up0.0266157091
GSE24585Down-0.0118642546
GSE37065Up0.0651697479
GSE28863_A1Up0.0645934085
GSE28863_A2Down-0.0232934775
GSE28863_A3Up0.2500957930
GSE28863_A4Up0.1151569654
GSE48662Up0.0782138979

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.