HCSGD entry for KIF5B
1. General information
| Official gene symbol | KIF5B |
|---|---|
| Entrez ID | 3799 |
| Gene full name | kinesin family member 5B |
| Other gene symbols | KINH KNS KNS1 UKHC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003777 | Microtubule motor activity | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005871 | Kinesin complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007018 | Microtubule-based movement | TAS | biological_process |
| GO:0007028 | Cytoplasm organization | IEA | biological_process |
| GO:0008017 | Microtubule binding | ISS | molecular_function |
| GO:0031982 | Vesicle | IDA | cellular_component |
| GO:0035253 | Ciliary rootlet | IEA | cellular_component |
| GO:0035617 | Stress granule disassembly | ISS | biological_process |
| GO:0042391 | Regulation of membrane potential | IDA | biological_process |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0043268 | Positive regulation of potassium ion transport | IDA | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0047496 | Vesicle transport along microtubule | ISS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | ISS | cellular_component |
| GO:0090004 | Positive regulation of establishment of protein localization to plasma membrane | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3557539113 | 0.6214543900 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0047224331 |
| GSE13712_SHEAR | Down | -0.0767478656 |
| GSE13712_STATIC | Down | -0.1297021702 |
| GSE19018 | Down | -0.1035998421 |
| GSE19899_A1 | Down | -0.0592257895 |
| GSE19899_A2 | Down | -0.2797757765 |
| PubMed_21979375_A1 | Down | -0.3933348106 |
| PubMed_21979375_A2 | Down | -0.4812219046 |
| GSE35957 | Up | 0.1773704116 |
| GSE36640 | Down | -0.0272890726 |
| GSE54402 | Down | -0.0240199012 |
| GSE9593 | Up | 0.2686514566 |
| GSE43922 | Down | -0.1405057422 |
| GSE24585 | Up | 0.1411449176 |
| GSE37065 | Down | -0.0251469673 |
| GSE28863_A1 | Up | 0.5200110914 |
| GSE28863_A2 | Up | 0.7670384941 |
| GSE28863_A3 | Up | 0.3357692377 |
| GSE28863_A4 | Up | 0.1979170999 |
| GSE48662 | Down | -0.0651051330 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT021905 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1 | MIMAT0000416 | MIRT023550 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024776 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025237 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026150 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027014 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028400 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031456 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031456 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031456 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044956 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
