HCSGD entry for KCNQ3

1. General information

Official gene symbolKCNQ3
Entrez ID3786
Gene full namepotassium voltage-gated channel, KQT-like subfamily, member 3
Other gene symbolsBFNC2 EBN2 KV7.3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005249Voltage-gated potassium channel activityIEA TASmolecular_function
GO:0005251Delayed rectifier potassium channel activityIBAmolecular_function
GO:0005267Potassium channel activityTASmolecular_function
GO:0005886Plasma membraneISS TAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0033268Node of RanvierISScellular_component
GO:0043194Axon initial segmentISScellular_component
GO:0060081Membrane hyperpolarizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13308354550.97146634630.73838364251.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0360946887
GSE13712_SHEARDown-0.0072882650
GSE13712_STATICDown-0.0435257419
GSE19018Up0.1762640856
GSE19899_A1Up0.1733166686
GSE19899_A2Up0.2421559592
PubMed_21979375_A1Up0.1910540806
PubMed_21979375_A2Up0.0276703274
GSE35957Up0.0786060795
GSE36640Up0.3500337612
GSE54402Down-0.0540331744
GSE9593Up0.2665475807
GSE43922Up0.5120763351
GSE24585Down-0.1272330397
GSE37065Up0.1588209121
GSE28863_A1Down-0.1141058288
GSE28863_A2Up0.4129425120
GSE28863_A3Up0.0621219037
GSE28863_A4Up0.0682948884
GSE48662Up0.4513216940

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DiclofenacDB00586 APRD00527
Meclofenamic acidDB00939 APRD01090
ICA-105665DB06089 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.