HCSGD entry for KCNN1

1. General information

Official gene symbolKCNN1
Entrez ID3780
Gene full namepotassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
Other gene symbolsKCa2.1 SK1 SKCA1 hSK1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexTAScellular_component
GO:0015269Calcium-activated potassium channel activityTASmolecular_function
GO:0016286Small conductance calcium-activated potassium channel activityIEAmolecular_function
GO:0034220Ion transmembrane transportTASbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
GO:0071805Potassium ion transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83742936060.47403315980.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0078282476
GSE13712_SHEARDown-0.3202227443
GSE13712_STATICDown-0.3684556501
GSE19018Down-0.0539910462
GSE19899_A1Up0.0088006832
GSE19899_A2Up0.2064022456
PubMed_21979375_A1Up0.1187668392
PubMed_21979375_A2Down-0.0073305257
GSE35957Up0.1702541414
GSE36640Up0.1343874168
GSE54402Down-0.0123536821
GSE9593Down-0.0431527034
GSE43922Up0.0325731959
GSE24585Up0.1458651926
GSE37065Down-0.0386184735
GSE28863_A1Down-0.1864238924
GSE28863_A2Down-0.2513453223
GSE28863_A3Up0.2253574713
GSE28863_A4Down-0.0806547913
GSE48662Up0.0044044548

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MiconazoleDB01110 APRD01115

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.