HCSGD entry for USP17L2

1. General information

Official gene symbolUSP17L2
Entrez ID377630
Gene full nameubiquitin specific peptidase 17-like family member 2
Other gene symbolsDUB-3 DUB3 USP17
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000075Cell cycle checkpointIMPbiological_process
GO:0004221Ubiquitin thiolesterase activityIMPmolecular_function
GO:0004843Ubiquitin-specific protease activityIDA IMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005789Endoplasmic reticulum membraneIDAcellular_component
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0007093Mitotic cell cycle checkpointIMPbiological_process
GO:0010955Negative regulation of protein processingIMPbiological_process
GO:0016579Protein deubiquitinationIDAbiological_process
GO:0030334Regulation of cell migrationIMPbiological_process
GO:0031064Negative regulation of histone deacetylationIMPbiological_process
GO:0032321Positive regulation of Rho GTPase activityIMPbiological_process
GO:0034261Negative regulation of Ras GTPase activityIDAbiological_process
GO:0042127Regulation of cell proliferationIMPbiological_process
GO:0042981Regulation of apoptotic processIMPbiological_process
GO:0050691Regulation of defense response to virus by hostIMPbiological_process
GO:0070536Protein K63-linked deubiquitinationIDA IMPbiological_process
GO:0071108Protein K48-linked deubiquitinationIMPbiological_process
GO:0071586CAAX-box protein processingIMPbiological_process
GO:0090315Negative regulation of protein targeting to membraneIMPbiological_process
GO:1900027Regulation of ruffle assemblyIMPbiological_process
GO:1900245Positive regulation of MDA-5 signaling pathwayIMPbiological_process
GO:1900246Positive regulation of RIG-I signaling pathwayIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68509360590.97027087120.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0442905703

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.