HCSGD entry for KCNK2
1. General information
| Official gene symbol | KCNK2 |
|---|---|
| Entrez ID | 3776 |
| Gene full name | potassium channel, subfamily K, member 2 |
| Other gene symbols | K2p2.1 TPKC1 TREK TREK-1 TREK1 hTREK-1c hTREK-1e |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005249 | Voltage-gated potassium channel activity | IEA | molecular_function |
| GO:0005267 | Potassium channel activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | IEA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8621782037 | 0.0000211162 | 0.9999902473 | 0.0084212121 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2535383453 |
| GSE13712_SHEAR | Up | 0.0346261929 |
| GSE13712_STATIC | Down | -0.0226718610 |
| GSE19018 | Down | -0.3042231154 |
| GSE19899_A1 | Down | -0.4427805303 |
| GSE19899_A2 | Down | -4.2876011490 |
| PubMed_21979375_A1 | Down | -6.7341480888 |
| PubMed_21979375_A2 | Down | -6.2847067643 |
| GSE35957 | Up | 0.8098682828 |
| GSE36640 | Down | -5.8042040425 |
| GSE54402 | Down | -3.1933614154 |
| GSE9593 | Up | 0.0856526535 |
| GSE43922 | Down | -3.4682197402 |
| GSE24585 | Down | -1.1594128263 |
| GSE37065 | Down | -0.1881251851 |
| GSE28863_A1 | Up | 0.3933556156 |
| GSE28863_A2 | Up | 1.0797402529 |
| GSE28863_A3 | Up | 0.3160543557 |
| GSE28863_A4 | Down | -0.2494851175 |
| GSE48662 | Down | -0.7597965235 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022916 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
