HCSGD entry for ARF1
1. General information
| Official gene symbol | ARF1 |
|---|---|
| Entrez ID | 375 |
| Gene full name | ADP-ribosylation factor 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0002090 | Regulation of receptor internalization | ISS | biological_process |
| GO:0003924 | GTPase activity | TAS | molecular_function |
| GO:0005057 | Receptor signaling protein activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006184 | GTP catabolic process | TAS | biological_process |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0006878 | Cellular copper ion homeostasis | IMP | biological_process |
| GO:0006890 | Retrograde vesicle-mediated transport, Golgi to ER | TAS | biological_process |
| GO:0006892 | Post-Golgi vesicle-mediated transport | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0030017 | Sarcomere | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0034315 | Regulation of Arp2/3 complex-mediated actin nucleation | ISS | biological_process |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0048205 | COPI coating of Golgi vesicle | TAS | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0050690 | Regulation of defense response to virus by virus | TAS | biological_process |
| GO:0060292 | Long term synaptic depression | ISS | biological_process |
| GO:0097061 | Dendritic spine organization | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2745872155 | 0.4434319707 | 0.9706433118 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3362409634 |
| GSE13712_SHEAR | Up | 1.0579679574 |
| GSE13712_STATIC | Up | 0.0681247592 |
| GSE19018 | Up | 0.1522249208 |
| GSE19899_A1 | Down | -0.1184346385 |
| GSE19899_A2 | Down | -0.3702345250 |
| PubMed_21979375_A1 | Down | -1.0653849272 |
| PubMed_21979375_A2 | Up | 0.6271061063 |
| GSE35957 | Up | 0.2531154597 |
| GSE36640 | Down | -0.4519959351 |
| GSE54402 | Up | 0.3774323932 |
| GSE9593 | Down | -0.3021206001 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0614442095 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 1,3-Propandiol | DB02774 | EXPT02534 |
| Glycerol | DB04077 | EXPT01027 |
| Guanosine-3'-Monophosphate-5'-Diphosphate | DB04121 | EXPT01529 |
| Guanosine-5'-Triphosphate | DB04137 | EXPT01660 |
| Guanosine-5'-Diphosphate | DB04315 | EXPT01573 |
| 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE | DB07348 | - |
| MYRISTIC ACID | DB08231 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-320b | MIMAT0005792 | MIRT036212 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038364 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040063 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043175 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046160 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047891 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049435 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
