HCSGD entry for NDUFS7
1. General information
| Official gene symbol | NDUFS7 |
|---|---|
| Entrez ID | 374291 |
| Gene full name | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) |
| Other gene symbols | CI-20 CI-20KD MY017 PSST |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002020 | Protease binding | IEA | molecular_function |
| GO:0003954 | NADH dehydrogenase activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005747 | Mitochondrial respiratory chain complex I | IDA IMP NAS | cellular_component |
| GO:0006120 | Mitochondrial electron transport, NADH to ubiquinone | NAS | biological_process |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | IEA NAS | molecular_function |
| GO:0016655 | Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | NAS | molecular_function |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0032981 | Mitochondrial respiratory chain complex I assembly | IMP | biological_process |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048038 | Quinone binding | IEA | molecular_function |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | IEA | molecular_function |
| GO:0097060 | Synaptic membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7128205539 | 0.4777787470 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0439996412 |
| GSE13712_SHEAR | Down | -0.0134575673 |
| GSE13712_STATIC | Down | -0.0657741759 |
| GSE19018 | Up | 0.0224534984 |
| GSE19899_A1 | Down | -0.1936230894 |
| GSE19899_A2 | Up | 0.3832402350 |
| PubMed_21979375_A1 | Up | 0.1040677597 |
| PubMed_21979375_A2 | Up | 0.3133947300 |
| GSE35957 | Down | -0.3288254940 |
| GSE36640 | Down | -0.0108335345 |
| GSE54402 | Down | -0.0146670564 |
| GSE9593 | Down | -0.1821775384 |
| GSE43922 | Up | 0.1085521417 |
| GSE24585 | Down | -0.4126021125 |
| GSE37065 | Down | -0.1893432706 |
| GSE28863_A1 | Down | -0.1868977510 |
| GSE28863_A2 | Down | -0.1133737041 |
| GSE28863_A3 | Up | 0.2014958660 |
| GSE28863_A4 | Up | 0.1810330084 |
| GSE48662 | Up | 0.0978295758 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028986 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037906 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-2-3p | MIMAT0004603 | MIRT038633 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
