HCSGD entry for KCNA2

1. General information

Official gene symbolKCNA2
Entrez ID3737
Gene full namepotassium voltage-gated channel, shaker-related subfamily, member 2
Other gene symbolsHBK5 HK4 HUKIV KV1.2 MK2 NGK1 RBK2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005249Voltage-gated potassium channel activityTASmolecular_function
GO:0005251Delayed rectifier potassium channel activityTASmolecular_function
GO:0005267Potassium channel activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0015271Outward rectifier potassium channel activityIEAmolecular_function
GO:0021633Optic nerve structural organizationIEAbiological_process
GO:0044224Juxtaparanode region of axonISScellular_component
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76271787170.71389387940.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0813634335
GSE13712_SHEARUp0.0205231179
GSE13712_STATICDown-0.0476813270
GSE19018Up0.1178978279
GSE19899_A1Down-0.0260086660
GSE19899_A2Up0.0356078413
PubMed_21979375_A1Down-0.2609892695
PubMed_21979375_A2Down-0.0787276747
GSE35957Up0.3617497352
GSE36640Up0.1206711052
GSE54402Down-0.0197092525
GSE9593Down-0.1531414660
GSE43922Up0.1459775345
GSE24585Down-0.3179223782
GSE37065Up0.0086178897
GSE28863_A1Down-0.0383081014
GSE28863_A2Up0.0284281590
GSE28863_A3Up0.2757912179
GSE28863_A4Up0.0252349728
GSE48662Up0.0492623210

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DalfampridineDB06637 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.