HCSGD entry for ITPA
1. General information
| Official gene symbol | ITPA |
|---|---|
| Entrez ID | 3704 |
| Gene full name | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) |
| Other gene symbols | C20orf37 HLC14-06-P dJ794I6.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006193 | ITP catabolic process | IEA | biological_process |
| GO:0009204 | Deoxyribonucleoside triphosphate catabolic process | IEA | biological_process |
| GO:0035870 | DITP diphosphatase activity | EXP | molecular_function |
| GO:0036220 | ITP diphosphatase activity | EXP | molecular_function |
| GO:0036222 | XTP diphosphatase activity | EXP | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051276 | Chromosome organization | IEA | biological_process |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8891309905 | 0.0341291136 | 0.9999902473 | 0.3489947164 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4169699103 |
| GSE13712_SHEAR | Down | -0.0733447339 |
| GSE13712_STATIC | Down | -0.0649930507 |
| GSE19018 | Down | -0.6414129923 |
| GSE19899_A1 | Down | -0.7047710484 |
| GSE19899_A2 | Up | 0.2383484139 |
| PubMed_21979375_A1 | Down | -0.1991171273 |
| PubMed_21979375_A2 | Down | -0.9229834695 |
| GSE35957 | Up | 0.0592673813 |
| GSE36640 | Down | -0.3261253704 |
| GSE54402 | Up | 0.3846121059 |
| GSE9593 | Down | -0.1240763399 |
| GSE43922 | Down | -0.1291928383 |
| GSE24585 | Down | -0.3916562174 |
| GSE37065 | Down | -0.1040087371 |
| GSE28863_A1 | Down | -0.0177996881 |
| GSE28863_A2 | Down | -0.3890974039 |
| GSE28863_A3 | Down | -0.1562850697 |
| GSE28863_A4 | Up | 0.1111777866 |
| GSE48662 | Down | -0.3074937510 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Citric Acid | DB04272 | EXPT00922 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-5p | MIMAT0000093 | MIRT048752 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
