HCSGD entry for ACADVL

1. General information

Official gene symbolACADVL
Entrez ID37
Gene full nameacyl-CoA dehydrogenase, very long chain
Other gene symbolsACAD6 LCACD VLCAD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001659Temperature homeostasisISSbiological_process
GO:0003995Acyl-CoA dehydrogenase activityIEA TASmolecular_function
GO:0004466Long-chain-acyl-CoA dehydrogenase activityTASmolecular_function
GO:0005739MitochondrionISScellular_component
GO:0005743Mitochondrial inner membraneIEAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0006635Fatty acid beta-oxidationTASbiological_process
GO:0006987Activation of signaling protein activity involved in unfolded protein responseTASbiological_process
GO:0015980Energy derivation by oxidation of organic compoundsTASbiological_process
GO:0016627Oxidoreductase activity, acting on the CH-CH group of donorsIEAmolecular_function
GO:0030968Endoplasmic reticulum unfolded protein responseTASbiological_process
GO:0033539Fatty acid beta-oxidation using acyl-CoA dehydrogenaseISSbiological_process
GO:0042645Mitochondrial nucleoidIDAcellular_component
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045717Negative regulation of fatty acid biosynthetic processISSbiological_process
GO:0046322Negative regulation of fatty acid oxidationISSbiological_process
GO:0050660Flavin adenine dinucleotide bindingIEAmolecular_function
GO:0090181Regulation of cholesterol metabolic processISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02021229820.88349682000.34236808241.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1384101796
GSE13712_SHEARDown-0.0782164304
GSE13712_STATICUp0.1496913260
GSE19018Up0.1214988521
GSE19899_A1Up0.4565152373
GSE19899_A2Up0.7213644197
PubMed_21979375_A1Up0.3972717471
PubMed_21979375_A2Up0.8035480765
GSE35957Down-1.0563543245
GSE36640Up0.1847408713
GSE54402Up0.2347790225
GSE9593Up0.0048795310
GSE43922Up0.3359596282
GSE24585Up0.9743211441
GSE37065Up0.1326019598
GSE28863_A1Up0.2353630240
GSE28863_A2Down-0.2675056483
GSE28863_A3Down-0.4685786161
GSE28863_A4Up0.1240242417
GSE48662Up0.2518581202

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022569MicroarrayFunctional MTI (Weak)18668037
hsa-miR-1MIMAT0000416MIRT023705ProteomicsFunctional MTI (Weak)18668040
hsa-miR-31-3pMIMAT0004504MIRT038930CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039914CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.