HCSGD entry for ITIH2

1. General information

Official gene symbolITIH2
Entrez ID3698
Gene full nameinter-alpha-trypsin inhibitor heavy chain 2
Other gene symbolsH2P SHAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004866Endopeptidase inhibitor activityTASmolecular_function
GO:0004867Serine-type endopeptidase inhibitor activityIEAmolecular_function
GO:0005576Extracellular regionNAScellular_component
GO:0010951Negative regulation of endopeptidase activityTASbiological_process
GO:0030212Hyaluronan metabolic processIEAbiological_process
GO:0052548Regulation of endopeptidase activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65291635580.76502910600.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0896892603
GSE13712_SHEARUp0.1410222774
GSE13712_STATICDown-0.2834941478
GSE19018Up0.1902164631
GSE19899_A1Up0.1254694343
GSE19899_A2Up0.0456187069
PubMed_21979375_A1Down-0.1933809575
PubMed_21979375_A2Up0.0762953829
GSE35957Up0.0926461139
GSE36640Up0.1129990077
GSE54402Down-0.1823382042
GSE9593Up0.1556702130
GSE43922Up0.0147879319
GSE24585Up0.0112875253
GSE37065Up0.0118576280
GSE28863_A1Down-0.0748367743
GSE28863_A2Down-0.0362206604
GSE28863_A3Up0.1619271580
GSE28863_A4Up0.0523186310
GSE48662Down-0.0199651982

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.