HCSGD entry for ITGB5
1. General information
| Official gene symbol | ITGB5 |
|---|---|
| Entrez ID | 3693 |
| Gene full name | integrin, beta 5 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002474 | Antigen processing and presentation of peptide antigen via MHC class I | TAS | biological_process |
| GO:0002479 | Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | TAS | biological_process |
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0005178 | Integrin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005925 | Focal adhesion | IEA | cellular_component |
| GO:0006936 | Muscle contraction | TAS | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007229 | Integrin-mediated signaling pathway | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0008305 | Integrin complex | IEA | cellular_component |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0031252 | Cell leading edge | IEA | cellular_component |
| GO:0042590 | Antigen processing and presentation of exogenous peptide antigen via MHC class I | TAS | biological_process |
| GO:0043235 | Receptor complex | IDA | cellular_component |
| GO:0045335 | Phagocytic vesicle | TAS | cellular_component |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0230735154 | 0.4936494092 | 0.3616227976 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6174193666 |
| GSE13712_SHEAR | Down | -0.0102262461 |
| GSE13712_STATIC | Up | 0.0540099890 |
| GSE19018 | Up | 0.9057062235 |
| GSE19899_A1 | Up | 0.0748148702 |
| GSE19899_A2 | Up | 0.0979172681 |
| PubMed_21979375_A1 | Down | -0.2536280845 |
| PubMed_21979375_A2 | Up | 0.2490565785 |
| GSE35957 | Up | 0.8267751797 |
| GSE36640 | Up | 1.5390597510 |
| GSE54402 | Down | -1.1302185381 |
| GSE9593 | Up | 0.8646014778 |
| GSE43922 | Up | 0.8457910116 |
| GSE24585 | Up | 0.0217485060 |
| GSE37065 | Up | 0.1125328731 |
| GSE28863_A1 | Up | 0.0885091443 |
| GSE28863_A2 | Up | 0.4194959215 |
| GSE28863_A3 | Down | -0.4262603221 |
| GSE28863_A4 | Down | -0.1675560124 |
| GSE48662 | Up | 0.2809473419 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018321 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020894 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051994 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
