HCSGD entry for ITGAX
1. General information
| Official gene symbol | ITGAX |
|---|---|
| Entrez ID | 3687 |
| Gene full name | integrin, alpha X (complement component 3 receptor 4 subunit) |
| Other gene symbols | CD11C SLEB6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007229 | Integrin-mediated signaling pathway | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008305 | Integrin complex | IEA | cellular_component |
| GO:0009887 | Organ morphogenesis | TAS | biological_process |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050900 | Leukocyte migration | TAS | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0859488545 | 0.9771777896 | 0.6150787928 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0694745851 |
| GSE13712_SHEAR | Up | 0.0211333530 |
| GSE13712_STATIC | Up | 0.0627081573 |
| GSE19018 | Up | 0.0367352449 |
| GSE19899_A1 | Up | 0.0582738161 |
| GSE19899_A2 | Up | 0.2385123902 |
| PubMed_21979375_A1 | Up | 1.1010342628 |
| PubMed_21979375_A2 | Up | 0.1890101445 |
| GSE35957 | Up | 0.2798876632 |
| GSE36640 | Up | 0.0519014612 |
| GSE54402 | Up | 0.4325538799 |
| GSE9593 | Down | -0.0270088323 |
| GSE43922 | Up | 0.9547420467 |
| GSE24585 | Up | 0.1333945366 |
| GSE37065 | Down | -0.0511785420 |
| GSE28863_A1 | Down | -0.0767905255 |
| GSE28863_A2 | Down | -0.0718141274 |
| GSE28863_A3 | Up | 0.2629204516 |
| GSE28863_A4 | Up | 0.0838771200 |
| GSE48662 | Down | -0.0415562799 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030204 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
