HCSGD entry for INSRR


1. General information

Official gene symbolINSRR
Entrez ID3645
Gene full nameinsulin receptor-related receptor
Other gene symbolsIRR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004714Transmembrane receptor protein tyrosine kinase activityIDA NASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0007169Transmembrane receptor protein tyrosine kinase signaling pathwayNASbiological_process
GO:0018108Peptidyl-tyrosine phosphorylationIDA NASbiological_process
GO:0030238Male sex determinationIEAbiological_process
GO:0031532Actin cytoskeleton reorganizationIDAbiological_process
GO:0043235Receptor complexIDAcellular_component
GO:0043548Phosphatidylinositol 3-kinase bindingIEAmolecular_function
GO:0043560Insulin receptor substrate bindingIEAmolecular_function
GO:0046777Protein autophosphorylationIMPbiological_process
GO:0071469Cellular response to alkalinityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31208054030.93886758100.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0243066848
GSE13712_SHEARUp0.3194703467
GSE13712_STATICUp0.0947653187
GSE19018Up0.0258777890
GSE19899_A1Up0.1625591057
GSE19899_A2Up0.1403467996
PubMed_21979375_A1Up0.1261154585
PubMed_21979375_A2Up0.2115732261
GSE35957Down-0.2202657875
GSE36640Up0.0234338983
GSE54402Up0.0489266585
GSE9593Up0.1364960466
GSE43922Up0.0175484776
GSE24585Up0.1878540396
GSE37065Up0.0856803919
GSE28863_A1Down-0.1270016451
GSE28863_A2Up0.0433456726
GSE28863_A3Up0.1850984524
GSE28863_A4Up0.0657565722
GSE48662Up0.2113954063

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.