HCSGD entry for INSRR
1. General information
| Official gene symbol | INSRR |
|---|---|
| Entrez ID | 3645 |
| Gene full name | insulin receptor-related receptor |
| Other gene symbols | IRR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004714 | Transmembrane receptor protein tyrosine kinase activity | IDA NAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005887 | Integral component of plasma membrane | NAS | cellular_component |
| GO:0007169 | Transmembrane receptor protein tyrosine kinase signaling pathway | NAS | biological_process |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | IDA NAS | biological_process |
| GO:0030238 | Male sex determination | IEA | biological_process |
| GO:0031532 | Actin cytoskeleton reorganization | IDA | biological_process |
| GO:0043235 | Receptor complex | IDA | cellular_component |
| GO:0043548 | Phosphatidylinositol 3-kinase binding | IEA | molecular_function |
| GO:0043560 | Insulin receptor substrate binding | IEA | molecular_function |
| GO:0046777 | Protein autophosphorylation | IMP | biological_process |
| GO:0071469 | Cellular response to alkalinity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3120805403 | 0.9388675810 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0243066848 |
| GSE13712_SHEAR | Up | 0.3194703467 |
| GSE13712_STATIC | Up | 0.0947653187 |
| GSE19018 | Up | 0.0258777890 |
| GSE19899_A1 | Up | 0.1625591057 |
| GSE19899_A2 | Up | 0.1403467996 |
| PubMed_21979375_A1 | Up | 0.1261154585 |
| PubMed_21979375_A2 | Up | 0.2115732261 |
| GSE35957 | Down | -0.2202657875 |
| GSE36640 | Up | 0.0234338983 |
| GSE54402 | Up | 0.0489266585 |
| GSE9593 | Up | 0.1364960466 |
| GSE43922 | Up | 0.0175484776 |
| GSE24585 | Up | 0.1878540396 |
| GSE37065 | Up | 0.0856803919 |
| GSE28863_A1 | Down | -0.1270016451 |
| GSE28863_A2 | Up | 0.0433456726 |
| GSE28863_A3 | Up | 0.1850984524 |
| GSE28863_A4 | Up | 0.0657565722 |
| GSE48662 | Up | 0.2113954063 |

