HCSGD entry for INPP5A
1. General information
| Official gene symbol | INPP5A |
|---|---|
| Entrez ID | 3632 |
| Gene full name | inositol polyphosphate-5-phosphatase, 40kDa |
| Other gene symbols | 5PTASE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004445 | Inositol-polyphosphate 5-phosphatase activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0016020 | Membrane | NAS | cellular_component |
| GO:0042731 | PH domain binding | IPI | molecular_function |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046856 | Phosphatidylinositol dephosphorylation | IEA | biological_process |
| GO:0052658 | Inositol-1,4,5-trisphosphate 5-phosphatase activity | IEA | molecular_function |
| GO:0052659 | Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6091562973 | 0.1316051442 | 0.9999902473 | 0.6992178204 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3012153945 |
| GSE13712_SHEAR | Up | 0.2381969739 |
| GSE13712_STATIC | Down | -0.1996911704 |
| GSE19018 | Up | 0.0817373988 |
| GSE19899_A1 | Down | -0.5294138113 |
| GSE19899_A2 | Up | 0.0106950669 |
| PubMed_21979375_A1 | Down | -0.1192139901 |
| PubMed_21979375_A2 | Down | -1.3568378801 |
| GSE35957 | Up | 0.6150677821 |
| GSE36640 | Up | 0.2108445111 |
| GSE54402 | Up | 0.2037410536 |
| GSE9593 | Up | 0.3664507075 |
| GSE43922 | Down | -0.1942559336 |
| GSE24585 | Down | -0.2615255666 |
| GSE37065 | Down | -0.1456331443 |
| GSE28863_A1 | Down | -0.0140318559 |
| GSE28863_A2 | Up | 0.0371872049 |
| GSE28863_A3 | Up | 0.0810561808 |
| GSE28863_A4 | Up | 0.1056824833 |
| GSE48662 | Down | -0.1385914627 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029103 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042796 | CLASH | Functional MTI (Weak) | 23622248 |
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