HCSGD entry for INPP5A


1. General information

Official gene symbolINPP5A
Entrez ID3632
Gene full nameinositol polyphosphate-5-phosphatase, 40kDa
Other gene symbols5PTASE
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004445Inositol-polyphosphate 5-phosphatase activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0016020MembraneNAScellular_component
GO:0042731PH domain bindingIPImolecular_function
GO:0043647Inositol phosphate metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046856Phosphatidylinositol dephosphorylationIEAbiological_process
GO:0052658Inositol-1,4,5-trisphosphate 5-phosphatase activityIEAmolecular_function
GO:0052659Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60915629730.13160514420.99999024730.6992178204

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3012153945
GSE13712_SHEARUp0.2381969739
GSE13712_STATICDown-0.1996911704
GSE19018Up0.0817373988
GSE19899_A1Down-0.5294138113
GSE19899_A2Up0.0106950669
PubMed_21979375_A1Down-0.1192139901
PubMed_21979375_A2Down-1.3568378801
GSE35957Up0.6150677821
GSE36640Up0.2108445111
GSE54402Up0.2037410536
GSE9593Up0.3664507075
GSE43922Down-0.1942559336
GSE24585Down-0.2615255666
GSE37065Down-0.1456331443
GSE28863_A1Down-0.0140318559
GSE28863_A2Up0.0371872049
GSE28863_A3Up0.0810561808
GSE28863_A4Up0.1056824833
GSE48662Down-0.1385914627

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029103MicroarrayFunctional MTI (Weak)19088304
hsa-miR-339-5pMIMAT0000764MIRT042796CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.