HCSGD entry for INHBA

1. General information

Official gene symbolINHBA
Entrez ID3624
Gene full nameinhibin, beta A
Other gene symbolsEDF FRP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleIDAbiological_process
GO:0001541Ovarian follicle developmentIGI NASbiological_process
GO:0001942Hair follicle developmentIGIbiological_process
GO:0002244Hematopoietic progenitor cell differentiationIDAbiological_process
GO:0005125Cytokine activityIDAmolecular_function
GO:0005179Hormone activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIDA TAScellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0006952Defense responseTASbiological_process
GO:0007050Cell cycle arrestIDAbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007399Nervous system developmentNASbiological_process
GO:0008083Growth factor activityTASmolecular_function
GO:0008285Negative regulation of cell proliferationIDAbiological_process
GO:0008584Male gonad developmentIGIbiological_process
GO:0010862Positive regulation of pathway-restricted SMAD protein phosphorylationIDAbiological_process
GO:0017046Peptide hormone bindingIPImolecular_function
GO:0030154Cell differentiationTASbiological_process
GO:0030218Erythrocyte differentiationNASbiological_process
GO:0030308Negative regulation of cell growthIDAbiological_process
GO:0032924Activin receptor signaling pathwayIDAbiological_process
GO:0040007GrowthIEAbiological_process
GO:0042326Negative regulation of phosphorylationTASbiological_process
GO:0042476OdontogenesisIGIbiological_process
GO:0042493Response to drugIDAbiological_process
GO:0042541Hemoglobin biosynthetic processIDAbiological_process
GO:0042701Progesterone secretionIGIbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0043509Activin A complexIDAcellular_component
GO:0043512Inhibin A complexIDAcellular_component
GO:0045077Negative regulation of interferon-gamma biosynthetic processTASbiological_process
GO:0045578Negative regulation of B cell differentiationTASbiological_process
GO:0045648Positive regulation of erythrocyte differentiationIDAbiological_process
GO:0045650Negative regulation of macrophage differentiationTASbiological_process
GO:0045786Negative regulation of cell cycleIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046880Regulation of follicle-stimulating hormone secretionIGIbiological_process
GO:0046881Positive regulation of follicle-stimulating hormone secretionTASbiological_process
GO:0046882Negative regulation of follicle-stimulating hormone secretionNASbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048333Mesodermal cell differentiationIEAbiological_process
GO:0060021Palate developmentIGIbiological_process
GO:0060279Positive regulation of ovulationISSbiological_process
GO:0061029Eyelid development in camera-type eyeISSbiological_process
GO:0070699Type II activin receptor bindingIPImolecular_function
GO:0071372Cellular response to follicle-stimulating hormone stimulusIEAbiological_process
GO:0071397Cellular response to cholesterolIEAbiological_process
GO:0097191Extrinsic apoptotic signaling pathwayIDAbiological_process
GO:2001241Positive regulation of extrinsic apoptotic signaling pathway in absence of ligandIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00266824970.27613503670.13915059291.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1469302520
GSE13712_SHEARDown-0.4929880727
GSE13712_STATICUp0.4152560785
GSE19018Down-0.0498652517
GSE19899_A1Up2.1668258973
GSE19899_A2Up0.6609764470
PubMed_21979375_A1Up1.4117524848
PubMed_21979375_A2Up1.9923682693
GSE35957Up0.2408653068
GSE36640Up0.2393022215
GSE54402Up0.8875087723
GSE9593Up0.6882808575
GSE43922Up1.3228725360
GSE24585Down-0.1880640957
GSE37065Up0.5195225750
GSE28863_A1Down-0.5629135727
GSE28863_A2Down-0.2963559129
GSE28863_A3Up0.3420138170
GSE28863_A4Down-0.3625878830
GSE48662Down-0.1358716244

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019457MicroarrayFunctional MTI (Weak)17612493
hsa-miR-31-3pMIMAT0004504MIRT038928CLASHFunctional MTI (Weak)23622248
hsa-miR-10b-5pMIMAT0000254MIRT047412CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.