HCSGD entry for AQP4

1. General information

Official gene symbolAQP4
Entrez ID361
Gene full nameaquaporin 4
Other gene symbolsHMIWC2 MIWC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityIEAmolecular_function
GO:0005372Water transmembrane transporter activityTASmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0005911Cell-cell junctionIEAcellular_component
GO:0006810TransportTASbiological_process
GO:0006833Water transportTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0007565Female pregnancyIEAbiological_process
GO:0007588ExcretionTASbiological_process
GO:0007605Sensory perception of soundIEAbiological_process
GO:0009314Response to radiationIEAbiological_process
GO:0009897External side of plasma membraneIDAcellular_component
GO:0015250Water channel activityEXPmolecular_function
GO:0015288Porin activityIEAmolecular_function
GO:0015670Carbon dioxide transportIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0030315T-tubuleIEAcellular_component
GO:0042538Hyperosmotic salinity responseIEAbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0050891Multicellular organismal water homeostasisIEPbiological_process
GO:0051260Protein homooligomerizationIEAbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0070295Renal water absorptionIEAbiological_process
GO:0071346Cellular response to interferon-gammaIDAbiological_process
GO:0071392Cellular response to estradiol stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83455251700.86396473920.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0362214103
GSE13712_SHEARDown-0.0913614613
GSE13712_STATICDown-0.0322473691
GSE19018Up0.0254409412
GSE19899_A1Up0.0617372500
GSE19899_A2Up0.0179249266
PubMed_21979375_A1Down-0.0620814908
PubMed_21979375_A2Up0.0176376261
GSE35957Up0.0478747995
GSE36640Up0.0399349708
GSE54402Down-0.0043672269
GSE9593Down-0.0786915945
GSE43922Up0.0151776538
GSE24585Up0.2912879623
GSE37065Down-0.0989524523
GSE28863_A1Down-0.0041597654
GSE28863_A2Down-0.0161701702
GSE28863_A3Up0.1612143861
GSE28863_A4Down-0.0044922736
GSE48662Up0.0275219832

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-320aMIMAT0000510MIRT006498Luciferase reporter assayFunctional MTI20628061
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.