HCSGD entry for AQP2

1. General information

Official gene symbolAQP2
Entrez ID359
Gene full nameaquaporin 2 (collecting duct)
Other gene symbolsAQP-CD WCH-CD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003097Renal water transportIEAbiological_process
GO:0003779Actin bindingIEAmolecular_function
GO:0005215Transporter activityIEAmolecular_function
GO:0005372Water transmembrane transporter activityIDAmolecular_function
GO:0005764LysosomeIEAcellular_component
GO:0005769Early endosomeIEAcellular_component
GO:0005791Rough endoplasmic reticulumIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005802Trans-Golgi networkIEAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006833Water transportIDA TASbiological_process
GO:0006884Cell volume homeostasisIEAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0006972Hyperosmotic responseIEAbiological_process
GO:0007565Female pregnancyIEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0007588ExcretionTASbiological_process
GO:0009651Response to salt stressIEAbiological_process
GO:0010226Response to lithium ionIEAbiological_process
GO:0015168Glycerol transmembrane transporter activityIDAmolecular_function
GO:0015250Water channel activityEXPmolecular_function
GO:0015793Glycerol transportIDAbiological_process
GO:0016020MembraneIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0016324Apical plasma membraneIDA ISScellular_component
GO:0030042Actin filament depolymerizationIEAbiological_process
GO:0030136Clathrin-coated vesicleIEAcellular_component
GO:0030165PDZ domain bindingIEAmolecular_function
GO:0030658Transport vesicle membraneTAScellular_component
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0033762Response to glucagonIEAbiological_process
GO:0034219Carbohydrate transmembrane transportIDAbiological_process
GO:0042594Response to starvationIEAbiological_process
GO:0042631Cellular response to water deprivationIEAbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0051592Response to calcium ionIEAbiological_process
GO:0051928Positive regulation of calcium ion transportIEAbiological_process
GO:0055037Recycling endosomeIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
GO:0070382Exocytic vesicleIEAcellular_component
GO:0071280Cellular response to copper ionIDAbiological_process
GO:0071288Cellular response to mercury ionIDAbiological_process
GO:0072205Metanephric collecting duct developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56915862240.90766858400.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0679380860
GSE13712_SHEARDown-0.0338003209
GSE13712_STATICDown-0.1916352901
GSE19018Up0.0823488817
GSE19899_A1Up0.0170964174
GSE19899_A2Up0.0944185272
PubMed_21979375_A1Down-0.0658392294
PubMed_21979375_A2Up0.0378874455
GSE35957Up0.1644506972
GSE36640Up0.0993716636
GSE54402Up0.0146533636
GSE9593Up0.1550985530
GSE43922Up0.0389943773
GSE24585Up0.0144051982
GSE37065Up0.1210359712
GSE28863_A1Down-0.0359028063
GSE28863_A2Down-0.0544004710
GSE28863_A3Up0.2572390500
GSE28863_A4Up0.0488622139
GSE48662Down-0.0060899442

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.