HCSGD entry for IK


1. General information

Official gene symbolIK
Entrez ID3550
Gene full nameIK cytokine, down-regulator of HLA II
Other gene symbolsCSA2 RED
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceTAScellular_component
GO:0005634NucleusIEAcellular_component
GO:0006955Immune responseTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0042802Identical protein bindingIPImolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69432517380.24618653550.99999024730.9549434526

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5689178098
GSE13712_SHEARDown-0.2971423569
GSE13712_STATICDown-0.1779002888
GSE19018Down-0.1055616723
GSE19899_A1Down-0.0863747334
GSE19899_A2Down-0.1070208342
PubMed_21979375_A1Down-0.3121221907
PubMed_21979375_A2Down-0.6096939688
GSE35957Down-0.1721560404
GSE36640Down-0.2201748093
GSE54402Up0.2226959516
GSE9593Down-0.0905657302
GSE43922Up0.0102385314
GSE24585Up0.2149079458
GSE37065Up0.1308965141
GSE28863_A1Up0.0799232236
GSE28863_A2Down-0.0419783941
GSE28863_A3Up0.2145421134
GSE28863_A4Up0.0235033081
GSE48662Down-0.5535975775

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT025539ProteomicsFunctional MTI (Weak)21566225
hsa-miR-92b-3pMIMAT0003218MIRT040554CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT048953CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.