HCSGD entry for IK
1. General information
| Official gene symbol | IK |
|---|---|
| Entrez ID | 3550 |
| Gene full name | IK cytokine, down-regulator of HLA II |
| Other gene symbols | CSA2 RED |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6943251738 | 0.2461865355 | 0.9999902473 | 0.9549434526 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5689178098 |
| GSE13712_SHEAR | Down | -0.2971423569 |
| GSE13712_STATIC | Down | -0.1779002888 |
| GSE19018 | Down | -0.1055616723 |
| GSE19899_A1 | Down | -0.0863747334 |
| GSE19899_A2 | Down | -0.1070208342 |
| PubMed_21979375_A1 | Down | -0.3121221907 |
| PubMed_21979375_A2 | Down | -0.6096939688 |
| GSE35957 | Down | -0.1721560404 |
| GSE36640 | Down | -0.2201748093 |
| GSE54402 | Up | 0.2226959516 |
| GSE9593 | Down | -0.0905657302 |
| GSE43922 | Up | 0.0102385314 |
| GSE24585 | Up | 0.2149079458 |
| GSE37065 | Up | 0.1308965141 |
| GSE28863_A1 | Up | 0.0799232236 |
| GSE28863_A2 | Down | -0.0419783941 |
| GSE28863_A3 | Up | 0.2145421134 |
| GSE28863_A4 | Up | 0.0235033081 |
| GSE48662 | Down | -0.5535975775 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025539 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040554 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048953 | CLASH | Functional MTI (Weak) | 23622248 |
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