HCSGD entry for IGLC1
1. General information
| Official gene symbol | IGLC1 |
|---|---|
| Entrez ID | 3537 |
| Gene full name | immunoglobulin lambda constant 1 (Mcg marker) |
| Other gene symbols | IGLC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003823 | Antigen binding | NAS | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006955 | Immune response | NAS | biological_process |
| GO:0006956 | Complement activation | TAS | biological_process |
| GO:0006958 | Complement activation, classical pathway | TAS | biological_process |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0050776 | Regulation of immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8697065499 | 0.8551552297 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0317298829 |
| GSE13712_SHEAR | Up | 0.0094400350 |
| GSE13712_STATIC | Down | -0.0781703516 |
| GSE19018 | Up | 0.0299757228 |
| GSE19899_A1 | Up | 0.0608292440 |
| GSE19899_A2 | Up | 0.0170108937 |
| PubMed_21979375_A1 | Up | 0.0143832612 |
| PubMed_21979375_A2 | Down | -0.0814906595 |
| GSE35957 | Up | 0.1082285710 |
| GSE36640 | Up | 0.0590170777 |
| GSE54402 | Up | 0.0366037506 |
| GSE9593 | Down | -0.2478964306 |
| GSE43922 | Up | 0.1536212785 |
| GSE24585 | Up | 0.0328639476 |
| GSE37065 | Down | -0.0533953090 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0446731030 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019074 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
