HCSGD entry for POLN


1. General information

Official gene symbolPOLN
Entrez ID353497
Gene full namepolymerase (DNA directed) nu
Other gene symbolsPOL4P
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003887DNA-directed DNA polymerase activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006281DNA repairIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67366585620.64980895480.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0896643524
GSE13712_SHEARDown-0.0974093071
GSE13712_STATICDown-0.2349489749
GSE19018Up0.2901938975
GSE19899_A1Up0.0331543538
GSE19899_A2Up0.0637081450
PubMed_21979375_A1Down-0.1052091271
PubMed_21979375_A2Up0.1970838561
GSE35957Up0.1984276594
GSE36640Up0.2477188365
GSE54402Up0.0622835887
GSE9593Up0.0176675417
GSE43922Up0.0684272499
GSE24585Down-0.2039553621
GSE37065Down-0.0015634238
GSE28863_A1Down-0.0700655412
GSE28863_A2Up0.2016166227
GSE28863_A3Down-0.3797366209
GSE28863_A4Down-0.1472335150
GSE48662Up0.0900671384

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017653MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.