HCSGD entry for IGHMBP2

1. General information

Official gene symbolIGHMBP2
Entrez ID3508
Gene full nameimmunoglobulin mu binding protein 2
Other gene symbolsCATF1 HCSA HMN6 SMARD1 SMUBP2 ZFAND7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000049TRNA bindingIDAmolecular_function
GO:0003677DNA bindingIDAmolecular_function
GO:0003678DNA helicase activityTASmolecular_function
GO:0003697Single-stranded DNA bindingTASmolecular_function
GO:0003723RNA bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006260DNA replicationTASbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006310DNA recombinationTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006412TranslationNASbiological_process
GO:0008094DNA-dependent ATPase activityIDAmolecular_function
GO:0008134Transcription factor bindingIPImolecular_function
GO:0008186RNA-dependent ATPase activityIDAmolecular_function
GO:0008219Cell deathIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0030424AxonISScellular_component
GO:0030426Growth coneISScellular_component
GO:0030529Ribonucleoprotein complexISScellular_component
GO:0032508DNA duplex unwindingIDA TASbiological_process
GO:0032575ATP-dependent 5'-3' RNA helicase activityIDAmolecular_function
GO:0032797SMN complexIDAcellular_component
GO:0043022Ribosome bindingIDAmolecular_function
GO:0043141ATP-dependent 5'-3' DNA helicase activityIDA IEAmolecular_function
GO:0051260Protein homooligomerizationIPIbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.14389946430.97768956730.75979494481.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0381557351
GSE13712_SHEARUp0.0483083603
GSE13712_STATICDown-0.0332865092
GSE19018Up0.0446280179
GSE19899_A1Up0.0661159498
GSE19899_A2Up0.6356253294
PubMed_21979375_A1Up1.0081826770
PubMed_21979375_A2Up0.4086499654
GSE35957Down-0.1290344994
GSE36640Up0.1875111097
GSE54402Up0.2080882549
GSE9593Up0.0486155736
GSE43922Up0.4052146546
GSE24585Down-0.0061485659
GSE37065Up0.0567403291
GSE28863_A1Down-0.0278989532
GSE28863_A2Up0.0693021776
GSE28863_A3Up0.1049263996
GSE28863_A4Up0.0406303288
GSE48662Up0.0295860737

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT028922MicroarrayFunctional MTI (Weak)19088304
hsa-miR-877-3pMIMAT0004950MIRT037182CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-3pMIMAT0002891MIRT040925CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-5pMIMAT0000072MIRT050680CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052253CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.