HCSGD entry for ACADS
1. General information
| Official gene symbol | ACADS |
|---|---|
| Entrez ID | 35 |
| Gene full name | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| Other gene symbols | ACAD3 SCAD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000062 | Fatty-acyl-CoA binding | IEA | molecular_function |
| GO:0003995 | Acyl-CoA dehydrogenase activity | IEA TAS | molecular_function |
| GO:0004085 | Butyryl-CoA dehydrogenase activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006635 | Fatty acid beta-oxidation | TAS | biological_process |
| GO:0031966 | Mitochondrial membrane | IEA | cellular_component |
| GO:0033539 | Fatty acid beta-oxidation using acyl-CoA dehydrogenase | IEA | biological_process |
| GO:0042594 | Response to starvation | IEA | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046359 | Butyrate catabolic process | IEA | biological_process |
| GO:0050660 | Flavin adenine dinucleotide binding | IEA | molecular_function |
| GO:0051289 | Protein homotetramerization | IEA | biological_process |
| GO:0051384 | Response to glucocorticoid | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8093415714 | 0.4615099958 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0215340044 |
| GSE13712_SHEAR | Up | 0.0709804132 |
| GSE13712_STATIC | Up | 0.2363401341 |
| GSE19018 | Up | 0.0769142046 |
| GSE19899_A1 | Down | -0.2167840283 |
| GSE19899_A2 | Down | -0.2994608447 |
| PubMed_21979375_A1 | Down | -0.4220136307 |
| PubMed_21979375_A2 | Down | -0.1351821862 |
| GSE35957 | Down | -0.1282566088 |
| GSE36640 | Down | -0.2045736108 |
| GSE54402 | Up | 0.0528553427 |
| GSE9593 | Up | 0.1320538113 |
| GSE43922 | Down | -0.0167939418 |
| GSE24585 | Up | 0.2658233801 |
| GSE37065 | Down | -0.1170571804 |
| GSE28863_A1 | Down | -0.0327114885 |
| GSE28863_A2 | Down | -0.0147558702 |
| GSE28863_A3 | Up | 0.0957375491 |
| GSE28863_A4 | Up | 0.0065637483 |
| GSE48662 | Up | 0.3012001708 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
| Acetoacetyl-Coenzyme A | DB03059 | EXPT00820 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029099 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-484 | MIMAT0002174 | MIRT041697 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049063 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
