HCSGD entry for HCN1

1. General information

Official gene symbolHCN1
Entrez ID348980
Gene full namehyperpolarization activated cyclic nucleotide-gated potassium channel 1
Other gene symbolsBCNG-1 BCNG1 HAC-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005222Intracellular cAMP activated cation channel activityISSmolecular_function
GO:0005249Voltage-gated potassium channel activityIBA ISSmolecular_function
GO:0005267Potassium channel activityNASmolecular_function
GO:0005272Sodium channel activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIBA ISScellular_component
GO:0006813Potassium ion transportNASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0016021Integral component of membraneNAScellular_component
GO:0030424AxonIEAcellular_component
GO:0030425DendriteIEAcellular_component
GO:0030552CAMP bindingISSmolecular_function
GO:0042391Regulation of membrane potentialIBAbiological_process
GO:0045176Apical protein localizationIEAbiological_process
GO:0046549Retinal cone cell developmentIEAbiological_process
GO:0071320Cellular response to cAMPISSbiological_process
GO:0071805Potassium ion transmembrane transportIBA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33913163250.88324788190.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0615517191
GSE13712_SHEARDown-0.0034712188
GSE13712_STATICUp0.1197865321
GSE19018Up0.1083272001
GSE19899_A1Up0.0283851155
GSE19899_A2Up0.0087468862
PubMed_21979375_A1Down-0.0134823287
PubMed_21979375_A2Up0.0855084411
GSE35957Up0.0149105202
GSE36640Down-0.0240387822
GSE54402Up0.0391627012
GSE9593Down-0.0132623217
GSE43922Up0.0739736307
GSE24585Down-0.0087842535
GSE37065Down-0.0280897816
GSE28863_A1Down-0.1583838651
GSE28863_A2Up1.4777498950
GSE28863_A3Up0.0633589219
GSE28863_A4Down-0.1429715160
GSE48662Up0.0924545451

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.