HCSGD entry for TUBB2B
1. General information
| Official gene symbol | TUBB2B |
|---|---|
| Entrez ID | 347733 |
| Gene full name | tubulin, beta 2B class IIb |
| Other gene symbols | PMGYSA bA506K6.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001764 | Neuron migration | IMP | biological_process |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0007017 | Microtubule-based process | IEA | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0051084 | 'de novo' posttranslational protein folding | TAS | biological_process |
| GO:0051258 | Protein polymerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9937310702 | 0.0006620721 | 0.9999902473 | 0.0481392265 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2523199692 |
| GSE13712_SHEAR | Down | -0.0461345056 |
| GSE13712_STATIC | Down | -0.5941684854 |
| GSE19018 | Down | -0.1191023621 |
| GSE19899_A1 | Down | -0.6808270062 |
| GSE19899_A2 | Down | -3.8928682389 |
| PubMed_21979375_A1 | Down | -3.9147405845 |
| PubMed_21979375_A2 | Down | -4.1823978785 |
| GSE35957 | Down | -1.2253806872 |
| GSE36640 | Down | -0.4079497940 |
| GSE54402 | Down | -0.3264647662 |
| GSE9593 | Down | -0.6827822494 |
| GSE43922 | Down | -0.1981924724 |
| GSE24585 | Down | -0.3941475039 |
| GSE37065 | Down | -0.3040988041 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0239525809 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| CYT997 | DB05147 | - |
| 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE | DB07574 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022690 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023769 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037235 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040215 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045115 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048981 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
