HCSGD entry for IFNGR2
1. General information
| Official gene symbol | IFNGR2 |
|---|---|
| Entrez ID | 3460 |
| Gene full name | interferon gamma receptor 2 (interferon gamma transducer 1) |
| Other gene symbols | AF-1 IFGR2 IFNGT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004906 | Interferon-gamma receptor activity | TAS | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007166 | Cell surface receptor signaling pathway | TAS | biological_process |
| GO:0009615 | Response to virus | TAS | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0060333 | Interferon-gamma-mediated signaling pathway | TAS | biological_process |
| GO:0060334 | Regulation of interferon-gamma-mediated signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3068726150 | 0.6942014969 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0025120012 |
| GSE13712_SHEAR | Down | -0.0451794209 |
| GSE13712_STATIC | Up | 0.0045522710 |
| GSE19018 | Down | -0.0058249119 |
| GSE19899_A1 | Up | 0.2276525529 |
| GSE19899_A2 | Up | 0.4205245721 |
| PubMed_21979375_A1 | Down | -0.0382368118 |
| PubMed_21979375_A2 | Up | 0.0478778008 |
| GSE35957 | Down | -0.1392394354 |
| GSE36640 | Up | 0.3011446772 |
| GSE54402 | Up | 0.4439604892 |
| GSE9593 | Up | 0.2585547921 |
| GSE43922 | Down | -0.0296948615 |
| GSE24585 | Up | 0.1402244521 |
| GSE37065 | Down | -0.1659286069 |
| GSE28863_A1 | Down | -0.0067348634 |
| GSE28863_A2 | Down | -0.1000011039 |
| GSE28863_A3 | Down | -0.1607138652 |
| GSE28863_A4 | Up | 0.1163499582 |
| GSE48662 | Down | -0.2089295978 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Interferon gamma-1b | DB00033 | BTD00017 | BIOD00017 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027145 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030035 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036154 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046534 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
