HCSGD entry for IRGM
1. General information
| Official gene symbol | IRGM |
|---|---|
| Entrez ID | 345611 |
| Gene full name | immunity-related GTPase family, M |
| Other gene symbols | IFI1 IRGM1 LRG-47 LRG47 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0000421 | Autophagic vacuole membrane | IEA | cellular_component |
| GO:0001891 | Phagocytic cup | IEA | cellular_component |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0006914 | Autophagy | IEA | biological_process |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016817 | Hydrolase activity, acting on acid anhydrides | IEA | molecular_function |
| GO:0030670 | Phagocytic vesicle membrane | IEA | cellular_component |
| GO:0042995 | Cell projection | IEA | cellular_component |
| GO:0045087 | Innate immune response | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6395543976 | 0.5933996619 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0427872140 |
| GSE13712_SHEAR | Down | -0.1846474292 |
| GSE13712_STATIC | Up | 0.1235422559 |
| GSE19018 | Down | -0.0848844669 |
| GSE19899_A1 | Up | 0.0683220383 |
| GSE19899_A2 | Up | 0.1608590339 |
| PubMed_21979375_A1 | Down | -0.3615457966 |
| PubMed_21979375_A2 | Up | 0.2430020324 |
| GSE35957 | Up | 0.0093510475 |
| GSE36640 | Down | -0.0131865073 |
| GSE54402 | Down | -0.1335347237 |
| GSE9593 | Up | 0.1370290073 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.0707197908 |
| GSE28863_A2 | Up | 0.0902915097 |
| GSE28863_A3 | Down | -0.1023356715 |
| GSE28863_A4 | Up | 0.2188370087 |
| GSE48662 | Down | -0.0394339453 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
