HCSGD entry for IFNA8

1. General information

Official gene symbolIFNA8
Entrez ID3445
Gene full nameinterferon, alpha 8
Other gene symbolsIFN-alphaB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002250Adaptive immune responseIBAbiological_process
GO:0002286T cell activation involved in immune responseIBAbiological_process
GO:0002323Natural killer cell activation involved in immune responseIBAbiological_process
GO:0005125Cytokine activityIBAmolecular_function
GO:0005126Cytokine receptor bindingTASmolecular_function
GO:0005132Type I interferon receptor bindingIBAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIBAcellular_component
GO:0006959Humoral immune responseIBAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0019221Cytokine-mediated signaling pathwayIBA TASbiological_process
GO:0030183B cell differentiationIBAbiological_process
GO:0033141Positive regulation of peptidyl-serine phosphorylation of STAT proteinIBAbiological_process
GO:0042100B cell proliferationIBAbiological_process
GO:0043330Response to exogenous dsRNAIBAbiological_process
GO:0045087Innate immune responseIBA TASbiological_process
GO:0045343Regulation of MHC class I biosynthetic processIBAbiological_process
GO:0051607Defense response to virusIEAbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
GO:0060338Regulation of type I interferon-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.37640518220.82607210590.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0839725506
GSE13712_SHEARUp0.0928217198
GSE13712_STATICDown-0.0708081463
GSE19018Up0.0586485532
GSE19899_A1Up0.2220911350
GSE19899_A2Down-0.3095909064
PubMed_21979375_A1Up0.0806274902
PubMed_21979375_A2Up0.1278651342
GSE35957Down-0.0219859603
GSE36640Up0.0748526475
GSE54402Down-0.0856377638
GSE9593Up0.0837815828
GSE43922Up0.0159805458
GSE24585Down-0.0191402240
GSE37065Down-0.0303735670
GSE28863_A1Up0.1725980358
GSE28863_A2Up0.0536875993
GSE28863_A3Up0.2909500817
GSE28863_A4Up0.1737245299
GSE48662Up0.0475921600

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.