HCSGD entry for APOC2

1. General information

Official gene symbolAPOC2
Entrez ID344
Gene full nameapolipoprotein C-II
Other gene symbolsAPO-CII APOC-II
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processTASbiological_process
GO:0005576Extracellular regionNAS TAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0005769Early endosomeTAScellular_component
GO:0006629Lipid metabolic processIEAbiological_process
GO:0006869Lipid transportIEAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0008047Enzyme activator activityIEAmolecular_function
GO:0008289Lipid bindingIDAmolecular_function
GO:0010518Positive regulation of phospholipase activityIDAbiological_process
GO:0010898Positive regulation of triglyceride catabolic processIDAbiological_process
GO:0010902Positive regulation of very-low-density lipoprotein particle remodelingICbiological_process
GO:0010916Negative regulation of very-low-density lipoprotein particle clearanceIDAbiological_process
GO:0016004Phospholipase activator activityIDAmolecular_function
GO:0016042Lipid catabolic processIEAbiological_process
GO:0032375Negative regulation of cholesterol transportIMPbiological_process
GO:0033344Cholesterol effluxIDAbiological_process
GO:0033700Phospholipid effluxIDAbiological_process
GO:0034361Very-low-density lipoprotein particleIDAcellular_component
GO:0034362Low-density lipoprotein particleIDAcellular_component
GO:0034363Intermediate-density lipoprotein particleIDAcellular_component
GO:0034366Spherical high-density lipoprotein particleIDAcellular_component
GO:0034370Triglyceride-rich lipoprotein particle remodelingTASbiological_process
GO:0034371Chylomicron remodelingICbiological_process
GO:0034372Very-low-density lipoprotein particle remodelingTASbiological_process
GO:0034382Chylomicron remnant clearanceIDAbiological_process
GO:0034384High-density lipoprotein particle clearanceIMPbiological_process
GO:0042157Lipoprotein metabolic processTASbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042627ChylomicronIDA IEAcellular_component
GO:0042632Cholesterol homeostasisICbiological_process
GO:0042803Protein homodimerization activityIMPmolecular_function
GO:0042953Lipoprotein transportIEAbiological_process
GO:0043086Negative regulation of catalytic activityIDAbiological_process
GO:0043274Phospholipase bindingIPImolecular_function
GO:0043691Reverse cholesterol transportICbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045723Positive regulation of fatty acid biosynthetic processIDAbiological_process
GO:0045833Negative regulation of lipid metabolic processIDAbiological_process
GO:0048261Negative regulation of receptor-mediated endocytosisIDAbiological_process
GO:0051006Positive regulation of lipoprotein lipase activityIDAbiological_process
GO:0055102Lipase inhibitor activityIDAmolecular_function
GO:0060230Lipoprotein lipase activator activityIDAmolecular_function
GO:0060697Positive regulation of phospholipid catabolic processIDAbiological_process
GO:0070328Triglyceride homeostasisIMPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66137193880.85950879150.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0872762801
GSE13712_SHEARDown-0.1818848317
GSE13712_STATICUp0.1292044256
GSE19018Up0.2081948294
GSE19899_A1Up0.0284075862
GSE19899_A2Up0.2809019462
PubMed_21979375_A1Down-0.2554453862
PubMed_21979375_A2Down-0.0074352018
GSE35957Up0.1316876477
GSE36640Up0.0097854511
GSE54402Down-0.1034380425
GSE9593Up0.0676426609
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.0389255328
GSE28863_A2Up0.0831862417
GSE28863_A3Up0.2561623885
GSE28863_A4Up0.1127587028
GSE48662Down-0.1337052704

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.