HCSGD entry for IFIT3
1. General information
| Official gene symbol | IFIT3 |
|---|---|
| Entrez ID | 3437 |
| Gene full name | interferon-induced protein with tetratricopeptide repeats 3 |
| Other gene symbols | CIG-49 GARG-49 IFI60 IFIT4 IRG2 ISG60 P60 RIG-G |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008285 | Negative regulation of cell proliferation | IDA | biological_process |
| GO:0009615 | Response to virus | IMP | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0035457 | Cellular response to interferon-alpha | IEA | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0043066 | Negative regulation of apoptotic process | IDA | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0060337 | Type I interferon signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0002514342 | 0.0370593405 | 0.0444836601 | 0.3629752788 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.3691192266 |
| GSE13712_SHEAR | Up | 5.3834131239 |
| GSE13712_STATIC | Up | 3.4730719100 |
| GSE19018 | Up | 0.2308578715 |
| GSE19899_A1 | Down | -0.4517312392 |
| GSE19899_A2 | Down | -0.6390305907 |
| PubMed_21979375_A1 | Down | -1.1711410243 |
| PubMed_21979375_A2 | Down | -0.1698029760 |
| GSE35957 | Down | -2.6596372207 |
| GSE36640 | Up | 2.0524652146 |
| GSE54402 | Down | -0.4165819554 |
| GSE9593 | Up | 1.6860790231 |
| GSE43922 | Down | -0.8865302433 |
| GSE24585 | Up | 1.9609971494 |
| GSE37065 | Up | 1.5888073719 |
| GSE28863_A1 | Down | -0.0903285312 |
| GSE28863_A2 | Up | 2.2078524817 |
| GSE28863_A3 | Down | -1.1581437513 |
| GSE28863_A4 | Up | 0.3860907697 |
| GSE48662 | Up | 0.1104135831 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-146a-5p | MIMAT0000449 | MIRT021277 | Microarray | Functional MTI (Weak) | 18057241 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022687 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023767 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040680 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
