HCSGD entry for IFIT1

1. General information

Official gene symbolIFIT1
Entrez ID3434
Gene full nameinterferon-induced protein with tetratricopeptide repeats 1
Other gene symbolsC56 G10P1 IFI-56 IFI-56K IFI56 IFIT-1 IFNAI1 ISG56 P56 RNM561
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003723RNA bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0009615Response to virusIDA IEA IMPbiological_process
GO:0019060Intracellular transport of viral protein in host cellIDAbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0032091Negative regulation of protein bindingIDAbiological_process
GO:0045070Positive regulation of viral genome replicationIDAbiological_process
GO:0045071Negative regulation of viral genome replicationIMPbiological_process
GO:0050688Regulation of defense response to virusIEAbiological_process
GO:0050689Negative regulation of defense response to virus by hostIDAbiological_process
GO:0051097Negative regulation of helicase activityIDAbiological_process
GO:0051607Defense response to virusIEAbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
GO:0071357Cellular response to type I interferonIDA IEAbiological_process
GO:0071360Cellular response to exogenous dsRNAIDA IEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00034998290.00108830210.05061483520.0626905908

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.3694618397
GSE13712_SHEARUp5.7475290733
GSE13712_STATICUp3.0945424554
GSE19018Up0.0878141914
GSE19899_A1Down-0.9947275095
GSE19899_A2Down-3.5027273250
PubMed_21979375_A1Down-4.3605010927
PubMed_21979375_A2Down-2.9179841617
GSE35957Down-2.7787085071
GSE36640Up2.2820289585
GSE54402Down-3.2558613842
GSE9593Up1.6027485869
GSE43922Down-2.0393756354
GSE24585Up2.0219893185
GSE37065Up1.9049075821
GSE28863_A1Up0.1009483886
GSE28863_A2Up1.4386889836
GSE28863_A3Down-0.9267519642
GSE28863_A4Up0.4082974828
GSE48662Up0.2625581460

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT020013MicroarrayFunctional MTI (Weak)20215506
hsa-miR-146a-5pMIMAT0000449MIRT021232MicroarrayFunctional MTI (Weak)18057241
hsa-miR-1MIMAT0000416MIRT024022MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.