HCSGD entry for IFI27
1. General information
| Official gene symbol | IFI27 |
|---|---|
| Entrez ID | 3429 |
| Gene full name | interferon, alpha-inducible protein 27 |
| Other gene symbols | FAM14D ISG12 ISG12A P27 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | TAS | cellular_component |
| GO:0006919 | Activation of cysteine-type endopeptidase activity involved in apoptotic process | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0060337 | Type I interferon signaling pathway | TAS | biological_process |
| GO:0097190 | Apoptotic signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0010270051 | 0.7058295316 | 0.0864207668 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.4811766113 |
| GSE13712_SHEAR | Up | 0.9727592991 |
| GSE13712_STATIC | Up | 1.7072871849 |
| GSE19018 | Up | 0.4249780933 |
| GSE19899_A1 | Down | -0.0061258715 |
| GSE19899_A2 | Down | -0.2054350425 |
| PubMed_21979375_A1 | Up | 0.3526806230 |
| PubMed_21979375_A2 | Down | -0.2062501762 |
| GSE35957 | Down | -4.3136420342 |
| GSE36640 | Up | 1.8505809835 |
| GSE54402 | Up | 0.0460969818 |
| GSE9593 | Up | 0.0688157058 |
| GSE43922 | Up | 0.0268812336 |
| GSE24585 | Up | 0.6713039740 |
| GSE37065 | Up | 1.2270380524 |
| GSE28863_A1 | Down | -0.0341502160 |
| GSE28863_A2 | Up | 2.5162529358 |
| GSE28863_A3 | Up | 0.4699501801 |
| GSE28863_A4 | Up | 0.0691505914 |
| GSE48662 | Up | 0.1839372496 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-146a-5p | MIMAT0000449 | MIRT021256 | Microarray | Functional MTI (Weak) | 18057241 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 11642719 | P27 expression was undetectable in subcapsular thymocytes with a tendency for increased expression toward the medulla |
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