HCSGD entry for IDUA

1. General information

Official gene symbolIDUA
Entrez ID3425
Gene full nameiduronidase, alpha-L-
Other gene symbolsIDA MPS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000902Cell morphogenesisIEAbiological_process
GO:0003940L-iduronidase activityIDA IEAmolecular_function
GO:0004553Hydrolase activity, hydrolyzing O-glycosyl compoundsIEAmolecular_function
GO:0005102Receptor bindingIEAmolecular_function
GO:0005764LysosomeIEAcellular_component
GO:0005975Carbohydrate metabolic processIEA TASbiological_process
GO:0005984Disaccharide metabolic processTASbiological_process
GO:0006027Glycosaminoglycan catabolic processIEA TASbiological_process
GO:0007040Lysosome organizationIEAbiological_process
GO:0030135Coated vesicleIEAcellular_component
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0030204Chondroitin sulfate metabolic processTASbiological_process
GO:0030207Chondroitin sulfate catabolic processTASbiological_process
GO:0030209Dermatan sulfate catabolic processIDAbiological_process
GO:0035108Limb morphogenesisIEAbiological_process
GO:0043202Lysosomal lumenTAScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048705Skeletal system morphogenesisIEAbiological_process
GO:0048878Chemical homeostasisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13887980700.87431554270.74952950581.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0028726355
GSE13712_SHEARDown-0.2088887721
GSE13712_STATICDown-0.2757741980
GSE19018Up0.0468768847
GSE19899_A1Up0.0298040683
GSE19899_A2Up0.2641932475
PubMed_21979375_A1Up0.3193011995
PubMed_21979375_A2Up0.2920666887
GSE35957Up0.0023672639
GSE36640Up0.6222582242
GSE54402Down-0.0672460099
GSE9593Up0.4436216934
GSE43922Up0.0484620188
GSE24585Down-0.0560597143
GSE37065Down-0.1113882161
GSE28863_A1Up0.0838698387
GSE28863_A2Up0.2685329663
GSE28863_A3Up0.3798498602
GSE28863_A4Down-0.1570656408
GSE48662Up0.5143602654

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016737MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.