HCSGD entry for IDH3G

1. General information

Official gene symbolIDH3G
Entrez ID3421
Gene full nameisocitrate dehydrogenase 3 (NAD+) gamma
Other gene symbolsH-IDHG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0004449Isocitrate dehydrogenase (NAD+) activityIEA ISSmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005739MitochondrionIDA ISScellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0005975Carbohydrate metabolic processNASbiological_process
GO:0006099Tricarboxylic acid cycleIEA TASbiological_process
GO:0006102Isocitrate metabolic processISSbiological_process
GO:0016616Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorIEAmolecular_function
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0051287NAD bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.36111874170.75608447250.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0854563802
GSE13712_SHEARDown-0.2995908771
GSE13712_STATICDown-0.1288371731
GSE19018Up0.2462864972
GSE19899_A1Down-0.1732504468
GSE19899_A2Up0.4783108318
PubMed_21979375_A1Up0.7974043233
PubMed_21979375_A2Up0.4279381901
GSE35957Down-0.2612430613
GSE36640Up0.2016295016
GSE54402Up0.3039474545
GSE9593Up0.0075280546
GSE43922Down-0.0112351163
GSE24585Up0.2021225991
GSE37065Down-0.0137477586
GSE28863_A1Down-0.1334820704
GSE28863_A2Down-0.1865797524
GSE28863_A3Down-0.2064035290
GSE28863_A4Up0.0224820281
GSE48662Up0.1502695257

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-320aMIMAT0000510MIRT044581CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.