HCSGD entry for RSPO2


1. General information

Official gene symbolRSPO2
Entrez ID340419
Gene full nameR-spondin 2
Other gene symbolsCRISTIN2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001649Osteoblast differentiationIEAbiological_process
GO:0005102Receptor bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0008201Heparin bindingIEAmolecular_function
GO:0009986Cell surfaceIEAcellular_component
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0030282Bone mineralizationIEAbiological_process
GO:0035115Embryonic forelimb morphogenesisIEAbiological_process
GO:0035116Embryonic hindlimb morphogenesisIEAbiological_process
GO:0060437Lung growthIEAbiological_process
GO:0060441Epithelial tube branching involved in lung morphogenesisIEAbiological_process
GO:0060535Trachea cartilage morphogenesisIEAbiological_process
GO:0090263Positive regulation of canonical Wnt signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84525948480.25008208270.99999024730.9601366103

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0371157135
GSE13712_SHEARUp0.0799117282
GSE13712_STATICDown-0.0216412556
GSE19018Down-0.1137916679
GSE19899_A1Down-0.0326302373
GSE19899_A2Down-0.0087767331
PubMed_21979375_A1Up0.1660338986
PubMed_21979375_A2Down-0.0030760776
GSE35957Up0.0489983676
GSE36640Up0.0377365568
GSE54402Up0.0975414090
GSE9593Down-0.0656621329
GSE43922Up0.0984024584
GSE24585Down-0.3622280803
GSE37065Up0.4464482677
GSE28863_A1Down-0.2259553404
GSE28863_A2Down-0.5928126602
GSE28863_A3Up0.1600717676
GSE28863_A4Down-0.0501540109
GSE48662Up0.0056775127

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018965MicroarrayFunctional MTI (Weak)18185580
hsa-miR-15a-3pMIMAT0004488MIRT038982CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.