HCSGD entry for KLHL17
1. General information
| Official gene symbol | KLHL17 |
|---|---|
| Entrez ID | 339451 |
| Gene full name | kelch-like family member 17 |
| Other gene symbols | RP11-54O7.6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0007420 | Brain development | IEA | biological_process |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | ISS | cellular_component |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0030036 | Actin cytoskeleton organization | ISS | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0031208 | POZ domain binding | IEA | molecular_function |
| GO:0032839 | Dendrite cytoplasm | IEA | cellular_component |
| GO:0032947 | Protein complex scaffold | ISS | molecular_function |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0051015 | Actin filament binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5213675012 | 0.7918927016 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0101033709 |
| GSE13712_SHEAR | Up | 0.1444586135 |
| GSE13712_STATIC | Up | 0.1154620290 |
| GSE19018 | Down | -0.0694721043 |
| GSE19899_A1 | Down | -0.1017697445 |
| GSE19899_A2 | Up | 0.2760389538 |
| PubMed_21979375_A1 | Up | 0.3987843247 |
| PubMed_21979375_A2 | Up | 0.2643419550 |
| GSE35957 | Down | -0.1622882655 |
| GSE36640 | Up | 0.1921943185 |
| GSE54402 | Up | 0.0556783950 |
| GSE9593 | Down | -0.0349358430 |
| GSE43922 | Up | 0.1253577401 |
| GSE24585 | Up | 0.0062506777 |
| GSE37065 | Down | -0.0648880485 |
| GSE28863_A1 | Down | -0.1993106224 |
| GSE28863_A2 | Up | 0.0068018836 |
| GSE28863_A3 | Up | 0.2858962308 |
| GSE28863_A4 | Down | -0.0096917686 |
| GSE48662 | Down | -0.3047401622 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018687 | Microarray | Functional MTI (Weak) | 18185580 |
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