HCSGD entry for KLHL17


1. General information

Official gene symbolKLHL17
Entrez ID339451
Gene full namekelch-like family member 17
Other gene symbolsRP11-54O7.6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0007420Brain developmentIEAbiological_process
GO:0014069Postsynaptic densityIEAcellular_component
GO:0015629Actin cytoskeletonISScellular_component
GO:0016567Protein ubiquitinationIEAbiological_process
GO:0030036Actin cytoskeleton organizationISSbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0031208POZ domain bindingIEAmolecular_function
GO:0032839Dendrite cytoplasmIEAcellular_component
GO:0032947Protein complex scaffoldISSmolecular_function
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0051015Actin filament bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52136750120.79189270160.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0101033709
GSE13712_SHEARUp0.1444586135
GSE13712_STATICUp0.1154620290
GSE19018Down-0.0694721043
GSE19899_A1Down-0.1017697445
GSE19899_A2Up0.2760389538
PubMed_21979375_A1Up0.3987843247
PubMed_21979375_A2Up0.2643419550
GSE35957Down-0.1622882655
GSE36640Up0.1921943185
GSE54402Up0.0556783950
GSE9593Down-0.0349358430
GSE43922Up0.1253577401
GSE24585Up0.0062506777
GSE37065Down-0.0648880485
GSE28863_A1Down-0.1993106224
GSE28863_A2Up0.0068018836
GSE28863_A3Up0.2858962308
GSE28863_A4Down-0.0096917686
GSE48662Down-0.3047401622

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018687MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.