HCSGD entry for ENPP7


1. General information

Official gene symbolENPP7
Entrez ID339221
Gene full nameectonucleotide pyrophosphatase/phosphodiesterase 7
Other gene symbolsALK-SMase
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003824Catalytic activityIEAmolecular_function
GO:0004767Sphingomyelin phosphodiesterase activityIDAmolecular_function
GO:0005794Golgi apparatusIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005902MicrovillusIDAcellular_component
GO:0006665Sphingolipid metabolic processTASbiological_process
GO:0006684Sphingomyelin metabolic processIDAbiological_process
GO:0006687Glycosphingolipid metabolic processTASbiological_process
GO:0008156Negative regulation of DNA replicationIDAbiological_process
GO:0008285Negative regulation of cell proliferationIDAbiological_process
GO:0016020MembraneNAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22002585010.88279112120.90191752291.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0166907260
GSE13712_SHEARUp0.0663851056
GSE13712_STATICUp0.1566008911
GSE19018Up0.4146126338
GSE19899_A1Down-0.1286742272
GSE19899_A2Up0.1034251091
PubMed_21979375_A1Down-0.0812259232
PubMed_21979375_A2Up0.0739730440
GSE35957Up0.2016647882
GSE36640Up0.1392706968
GSE54402Up0.0398354454
GSE9593Down-0.0885881355
GSE43922Up0.0507780129
GSE24585Down-0.0907628212
GSE37065Up0.0358195346
GSE28863_A1Down-0.1684180535
GSE28863_A2Up0.0189515441
GSE28863_A3Up0.5265854921
GSE28863_A4Up0.2752684088
GSE48662Down-0.0702344699

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.