HCSGD entry for ICA1


1. General information

Official gene symbolICA1
Entrez ID3382
Gene full nameislet cell autoantigen 1, 69kDa
Other gene symbolsICA69 ICAp69
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIDAcellular_component
GO:0003674Molecular_functionNDmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIEA ISScellular_component
GO:0006836Neurotransmitter transportIEAbiological_process
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0030658Transport vesicle membraneIEAcellular_component
GO:0030667Secretory granule membraneIDAcellular_component
GO:0030672Synaptic vesicle membraneIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63616609550.76394445500.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0386619347
GSE13712_SHEARDown-0.2503721834
GSE13712_STATICDown-0.0850060180
GSE19018Up0.1583231151
GSE19899_A1Up0.1038114171
GSE19899_A2Down-0.0009765055
PubMed_21979375_A1Down-0.0639372216
PubMed_21979375_A2Down-0.0942438348
GSE35957Up0.0641991170
GSE36640Up0.0845252577
GSE54402Up0.0519925487
GSE9593Down-0.0247353707
GSE43922Up0.0216926083
GSE24585Up0.8129697430
GSE37065Down-0.0455159916
GSE28863_A1Down-0.1163742879
GSE28863_A2Down-0.0546736288
GSE28863_A3Up0.1536285785
GSE28863_A4Up0.0211513670
GSE48662Down-0.1401307591

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.