HCSGD entry for HYAL1

1. General information

Official gene symbolHYAL1
Entrez ID3373
Gene full namehyaluronoglucosaminidase 1
Other gene symbolsHYAL-1 LUCA1 NAT6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000302Response to reactive oxygen speciesIDAbiological_process
GO:0001618Virus receptor activityIDAmolecular_function
GO:0004415Hyalurononglucosaminidase activityIDA IEAmolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005764LysosomeIDAcellular_component
GO:0005975Carbohydrate metabolic processIEA TASbiological_process
GO:0006954Inflammatory responseIDAbiological_process
GO:0008134Transcription factor bindingIDAmolecular_function
GO:0009615Response to virusIDA IEAbiological_process
GO:0010634Positive regulation of epithelial cell migrationIDAbiological_process
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0030204Chondroitin sulfate metabolic processTASbiological_process
GO:0030207Chondroitin sulfate catabolic processTASbiological_process
GO:0030212Hyaluronan metabolic processIDA TASbiological_process
GO:0030213Hyaluronan biosynthetic processIDAbiological_process
GO:0030214Hyaluronan catabolic processIDA TASbiological_process
GO:0030307Positive regulation of cell growthIMPbiological_process
GO:0030308Negative regulation of cell growthIDAbiological_process
GO:0031410Cytoplasmic vesicleIDAcellular_component
GO:0036117Hyaluranon cableIDAcellular_component
GO:0036120Cellular response to platelet-derived growth factor stimulusIDAbiological_process
GO:0043202Lysosomal lumenTAScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0044344Cellular response to fibroblast growth factor stimulusIDAbiological_process
GO:0045766Positive regulation of angiogenesisIDA IMPbiological_process
GO:0045785Positive regulation of cell adhesionIMPbiological_process
GO:0045927Positive regulation of growthIDAbiological_process
GO:0046677Response to antibioticIDAbiological_process
GO:0050501Hyaluronan synthase activityIDAmolecular_function
GO:0050679Positive regulation of epithelial cell proliferationIDAbiological_process
GO:0051216Cartilage developmentIEPbiological_process
GO:0060272Embryonic skeletal joint morphogenesisIEAbiological_process
GO:0071347Cellular response to interleukin-1IDAbiological_process
GO:0071356Cellular response to tumor necrosis factorIEPbiological_process
GO:0071467Cellular response to pHIDAbiological_process
GO:0071493Cellular response to UV-BIDAbiological_process
GO:1900106Positive regulation of hyaluranon cable assemblyIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87070624980.19189680860.99999024730.8508943463

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1583461389
GSE13712_SHEARDown-1.6921015800
GSE13712_STATICDown-0.2014972100
GSE19018Down-0.0462560052
GSE19899_A1Down-0.1006577981
GSE19899_A2Up0.1657697457
PubMed_21979375_A1Down-0.2765114661
PubMed_21979375_A2Down-0.1038241584
GSE35957Down-0.1188525496
GSE36640Up0.1696215795
GSE54402Up0.1153431067
GSE9593Down-0.0476389951
GSE43922Up0.0757837009
GSE24585Up0.1303007559
GSE37065Up0.1314941021
GSE28863_A1Up0.0482283451
GSE28863_A2Up0.2169360266
GSE28863_A3Down-0.3629452852
GSE28863_A4Up0.0094539825
GSE48662--

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-25-3pMIMAT0000081MIRT050233CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.