HCSGD entry for HUS1

1. General information

Official gene symbolHUS1
Entrez ID3364
Gene full nameHUS1 checkpoint homolog (S. pombe)
Other gene symbolshHUS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000077DNA damage checkpointIEA IMPbiological_process
GO:0000724Double-strand break repair via homologous recombinationIEAbiological_process
GO:0001932Regulation of protein phosphorylationIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDA IEAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0006260DNA replicationTASbiological_process
GO:0006281DNA repairIEA TASbiological_process
GO:0006468Protein phosphorylationIEAbiological_process
GO:0006974Cellular response to DNA damage stimulusTASbiological_process
GO:0007093Mitotic cell cycle checkpointIEAbiological_process
GO:0008156Negative regulation of DNA replicationIEAbiological_process
GO:0009411Response to UVIEAbiological_process
GO:0009790Embryo developmentIEAbiological_process
GO:0030896Checkpoint clamp complexIEAcellular_component
GO:0071479Cellular response to ionizing radiationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03972301200.91406093990.44796461011.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2219354653
GSE13712_SHEARUp0.5623304913
GSE13712_STATICUp0.4116306668
GSE19018Down-0.5698667488
GSE19899_A1Up0.1592959586
GSE19899_A2Up0.9283233349
PubMed_21979375_A1Up0.3112926808
PubMed_21979375_A2Up0.3242575350
GSE35957Up0.1450428843
GSE36640Up0.1889053655
GSE54402Up0.2827071481
GSE9593Up0.2168702092
GSE43922Up0.4470610766
GSE24585Down-0.0188523915
GSE37065Up0.1467265590
GSE28863_A1Up0.0447110750
GSE28863_A2Up0.4315788147
GSE28863_A3Down-0.3258941130
GSE28863_A4Down-0.1927835156
GSE48662Down-0.2775193853

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30c-5pMIMAT0000244MIRT047873CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.