HCSGD entry for HTR7
1. General information
| Official gene symbol | HTR7 |
|---|---|
| Entrez ID | 3363 |
| Gene full name | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| Other gene symbols | 5-HT7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004993 | Serotonin receptor activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006939 | Smooth muscle contraction | IEA | biological_process |
| GO:0007187 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | TAS | biological_process |
| GO:0007210 | Serotonin receptor signaling pathway | TAS | biological_process |
| GO:0007268 | Synaptic transmission | IEA | biological_process |
| GO:0007623 | Circadian rhythm | IEA | biological_process |
| GO:0008015 | Blood circulation | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0042310 | Vasoconstriction | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0075211390 | 0.8693662323 | 0.2267627721 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3184093099 |
| GSE13712_SHEAR | Up | 0.0044966152 |
| GSE13712_STATIC | Down | -0.1160605648 |
| GSE19018 | Down | -0.1443861996 |
| GSE19899_A1 | Up | 0.4351498445 |
| GSE19899_A2 | Up | 1.2962400968 |
| PubMed_21979375_A1 | Up | 1.8657040151 |
| PubMed_21979375_A2 | Up | 0.8830762490 |
| GSE35957 | Down | -0.2858066201 |
| GSE36640 | Up | 1.0849871073 |
| GSE54402 | Up | 1.5992910183 |
| GSE9593 | Up | 0.1201024310 |
| GSE43922 | Up | 1.8895254054 |
| GSE24585 | Down | -0.2266903743 |
| GSE37065 | Up | 0.0824285564 |
| GSE28863_A1 | Down | -0.1506931405 |
| GSE28863_A2 | Down | -0.2419091872 |
| GSE28863_A3 | Down | -0.0051735392 |
| GSE28863_A4 | Up | 0.0094249107 |
| GSE48662 | Down | -0.1599793972 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Eletriptan | DB00216 | APRD00945 |
| Ziprasidone | DB00246 | APRD00540 |
| Olanzapine | DB00334 | APRD00138 |
| Clozapine | DB00363 | APRD00470 |
| Mirtazapine | DB00370 | APRD00685 |
| Loxapine | DB00408 | APRD00574 |
| Amoxapine | DB00543 | APRD00142 |
| Epinastine | DB00751 | APRD00043 |
| Maprotiline | DB00934 | APRD00747 |
| Quetiapine | DB01224 | APRD00675 |
| Aripiprazole | DB01238 | APRD00638 |
| Iloperidone | DB04946 | - |
| Mianserin | DB06148 | - |
| Asenapine | DB06216 | - |
| Amisulpride | DB06288 | - |
| Lurasidone | DB08815 | - |
| Vortioxetine | DB09068 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016917 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
