HCSGD entry for HTR5A

1. General information

Official gene symbolHTR5A
Entrez ID3361
Gene full name5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
Other gene symbols5-HT5A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004993Serotonin receptor activityIDAmolecular_function
GO:0005791Rough endoplasmic reticulumIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerIEAbiological_process
GO:0007210Serotonin receptor signaling pathwayIDAbiological_process
GO:0019933CAMP-mediated signalingIEAbiological_process
GO:0021766Hippocampus developmentIEAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0032355Response to estradiolIEAbiological_process
GO:0043204PerikaryonIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.32317986780.87982050450.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1154091406
GSE13712_SHEARDown-0.2342538008
GSE13712_STATICDown-0.0760103490
GSE19018Up0.1676651547
GSE19899_A1Down-0.0172271032
GSE19899_A2Up0.2211389332
PubMed_21979375_A1Up0.1177158922
PubMed_21979375_A2Up0.0333660022
GSE35957Up0.3313471752
GSE36640Down-0.0725705309
GSE54402Up0.1730148957
GSE9593Down-0.0556430369
GSE43922Up0.0164965994
GSE24585Up0.6865482097
GSE37065Up0.0392990866
GSE28863_A1Down-0.0429963466
GSE28863_A2Up0.0287768011
GSE28863_A3Up0.1148277512
GSE28863_A4Up0.1103915152
GSE48662Up0.0601063297

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

OlanzapineDB00334 APRD00138
LoxapineDB00408 APRD00574
AsenapineDB06216 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.