HCSGD entry for HTR1B

1. General information

Official gene symbolHTR1B
Entrez ID3351
Gene full name5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
Other gene symbols5-HT1B 5-HT1DB HTR1D2 HTR1DB S12
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002031G-protein coupled receptor internalizationIEAbiological_process
GO:0004993Serotonin receptor activityIDAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIMPcellular_component
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007198Adenylate cyclase-inhibiting serotonin receptor signaling pathwayIDAbiological_process
GO:0007205Protein kinase C-activating G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007268Synaptic transmissionIEAbiological_process
GO:0008144Drug bindingIEAmolecular_function
GO:0014059Regulation of dopamine secretionIEAbiological_process
GO:0014063Negative regulation of serotonin secretionISSbiological_process
GO:0030818Negative regulation of cAMP biosynthetic processIDAbiological_process
GO:0032229Negative regulation of synaptic transmission, GABAergicIEAbiological_process
GO:0035690Cellular response to drugIDAbiological_process
GO:0042220Response to cocaineIEAbiological_process
GO:0042310VasoconstrictionIEAbiological_process
GO:0042756Drinking behaviorIEAbiological_process
GO:0045471Response to ethanolIEAbiological_process
GO:0046849Bone remodelingIEAbiological_process
GO:0050795Regulation of behaviorIEAbiological_process
GO:0051378Serotonin bindingIEAmolecular_function
GO:0051385Response to mineralocorticoidIEAbiological_process
GO:0051967Negative regulation of synaptic transmission, glutamatergicIEAbiological_process
GO:0071312Cellular response to alkaloidIDAbiological_process
GO:0071502Cellular response to temperature stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86797195400.34368534250.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1330445972
GSE13712_SHEARDown-0.1822049523
GSE13712_STATICDown-0.0651314234
GSE19018Down-0.1059972426
GSE19899_A1Up0.0169383185
GSE19899_A2Down-0.0698769944
PubMed_21979375_A1Up0.1537133472
PubMed_21979375_A2Down-0.4174064083
GSE35957Down-0.0017169179
GSE36640Down-0.2501123539
GSE54402Down-0.0548455430
GSE9593Up0.0374363615
GSE43922Up0.0485563117
GSE24585Down-0.1178336356
GSE37065Down-0.0826944805
GSE28863_A1Down-0.1715330804
GSE28863_A2Up0.0674929216
GSE28863_A3Up0.4133495698
GSE28863_A4Up0.0366844225
GSE48662Up0.1691729870

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-96-5pMIMAT0000095MIRT002447Reporter assayFunctional MTI18283276
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-96-5pMIMAT00000951hsa-miR-9618283276
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.