HCSGD entry for DNAJB2

1. General information

Official gene symbolDNAJB2
Entrez ID3300
Gene full nameDnaJ (Hsp40) homolog, subfamily B, member 2
Other gene symbolsDSMA5 HSJ-1 HSJ1 HSPF3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000502Proteasome complexIDAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0006457Protein foldingTASbiological_process
GO:0006986Response to unfolded proteinTASbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0008285Negative regulation of cell proliferationIGIbiological_process
GO:0016234Inclusion bodyIDAcellular_component
GO:0030308Negative regulation of cell growthIGIbiological_process
GO:0030433ER-associated ubiquitin-dependent protein catabolic processIDAbiological_process
GO:0030544Hsp70 protein bindingIPImolecular_function
GO:0031398Positive regulation of protein ubiquitinationIDAbiological_process
GO:0031593Polyubiquitin bindingIDAmolecular_function
GO:0032436Positive regulation of proteasomal ubiquitin-dependent protein catabolic processIDAbiological_process
GO:0051082Unfolded protein bindingTASmolecular_function
GO:0070628Proteasome bindingIDAmolecular_function
GO:0090084Negative regulation of inclusion body assemblyIDAbiological_process
GO:0090086Negative regulation of protein deubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.50937723870.23435414690.99999024730.9323511941

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0697430316
GSE13712_SHEARUp0.2619196843
GSE13712_STATICDown-0.2186507933
GSE19018Up0.1401746671
GSE19899_A1Down-0.3024458543
GSE19899_A2Down-0.1877763797
PubMed_21979375_A1Down-1.1850843232
PubMed_21979375_A2Down-0.0456734188
GSE35957Down-0.1459152453
GSE36640Up0.5313622128
GSE54402Down-0.5548133084
GSE9593Up0.2525013725
GSE43922Up0.0545617545
GSE24585Up0.0420676517
GSE37065Down-0.1313384369
GSE28863_A1Up0.1046805799
GSE28863_A2Up0.2594731761
GSE28863_A3Up0.0779465201
GSE28863_A4Down-0.1716464535
GSE48662Up0.5662048935

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT042091CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.