HCSGD entry for HSD11B2
1. General information
| Official gene symbol | HSD11B2 |
|---|---|
| Entrez ID | 3291 |
| Gene full name | hydroxysteroid (11-beta) dehydrogenase 2 |
| Other gene symbols | AME AME1 HSD11K HSD2 SDR9C3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001666 | Response to hypoxia | IEA | biological_process |
| GO:0002017 | Regulation of blood volume by renal aldosterone | IEA | biological_process |
| GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity | IEA | molecular_function |
| GO:0005496 | Steroid binding | IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0006704 | Glucocorticoid biosynthetic process | TAS | biological_process |
| GO:0007565 | Female pregnancy | IEA | biological_process |
| GO:0032094 | Response to food | IEA | biological_process |
| GO:0032868 | Response to insulin | IEA | biological_process |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0051287 | NAD binding | IEA | molecular_function |
| GO:0051384 | Response to glucocorticoid | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7125381141 | 0.8594325672 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0129701943 |
| GSE13712_SHEAR | Down | -0.1201229343 |
| GSE13712_STATIC | Up | 0.1497557126 |
| GSE19018 | Down | -0.1157221072 |
| GSE19899_A1 | Up | 0.0327649342 |
| GSE19899_A2 | Down | -0.0799746766 |
| PubMed_21979375_A1 | Up | 0.0390495203 |
| PubMed_21979375_A2 | Down | -0.1645654948 |
| GSE35957 | Down | -0.0329354059 |
| GSE36640 | Down | -0.0360363768 |
| GSE54402 | Down | -0.0355351739 |
| GSE9593 | Up | 0.1129403463 |
| GSE43922 | Up | 0.0564579078 |
| GSE24585 | Down | -0.0506529928 |
| GSE37065 | Up | 0.0464382837 |
| GSE28863_A1 | Up | 0.0006588116 |
| GSE28863_A2 | Up | 0.1083223222 |
| GSE28863_A3 | Up | 0.2546336141 |
| GSE28863_A4 | Up | 0.0781806045 |
| GSE48662 | Up | 0.1531154674 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
