HCSGD entry for HSD3B2

1. General information

Official gene symbolHSD3B2
Entrez ID3284
Gene full namehydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Other gene symbolsHSD3B HSDB SDR11E2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00038543-beta-hydroxy-delta5-steroid dehydrogenase activityIDA IEAmolecular_function
GO:0004769Steroid delta-isomerase activityIDAmolecular_function
GO:0005743Mitochondrial inner membraneISScellular_component
GO:0005758Mitochondrial intermembrane spaceISScellular_component
GO:0005783Endoplasmic reticulumNAScellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006694Steroid biosynthetic processIDA IEAbiological_process
GO:0006702Androgen biosynthetic processTASbiological_process
GO:0006704Glucocorticoid biosynthetic processTASbiological_process
GO:0006705Mineralocorticoid biosynthetic processTASbiological_process
GO:0008202Steroid metabolic processTASbiological_process
GO:0016021Integral component of membraneNAScellular_component
GO:0030868Smooth endoplasmic reticulum membraneISScellular_component
GO:0031966Mitochondrial membraneNAScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61672527260.86193546980.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0015238315
GSE13712_SHEARDown-0.1484807228
GSE13712_STATICUp0.0167357291
GSE19018Up0.0454693212
GSE19899_A1Up0.1362486403
GSE19899_A2Up0.0469434191
PubMed_21979375_A1Down-0.1174536881
PubMed_21979375_A2Down-0.0244607795
GSE35957Up0.1034628084
GSE36640Down-0.0803264717
GSE54402Up0.1534979811
GSE9593Up0.2597523967
GSE43922Down-0.0301154389
GSE24585Up0.0562209006
GSE37065Down-0.0579318632
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0919973656

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527
TrilostaneDB01108 APRD01276

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018040MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.