HCSGD entry for AGFG1
1. General information
| Official gene symbol | AGFG1 |
|---|---|
| Entrez ID | 3267 |
| Gene full name | ArfGAP with FG repeats 1 |
| Other gene symbols | HRB RAB RIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005643 | Nuclear pore | TAS | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0008060 | ARF GTPase activator activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IEA | cellular_component |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0032312 | Regulation of ARF GTPase activity | IEA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6210252612 | 0.2738817180 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3543124826 |
| GSE13712_SHEAR | Up | 0.0001633442 |
| GSE13712_STATIC | Up | 0.1172916222 |
| GSE19018 | Down | -0.2179399388 |
| GSE19899_A1 | Down | -0.1288728378 |
| GSE19899_A2 | Down | -0.0528725030 |
| PubMed_21979375_A1 | Up | 0.5598228492 |
| PubMed_21979375_A2 | Down | -0.4507541725 |
| GSE35957 | Up | 0.2793410262 |
| GSE36640 | Down | -0.1445277273 |
| GSE54402 | Down | -0.0658713946 |
| GSE9593 | Up | 0.0124650424 |
| GSE43922 | Down | -0.0000878935 |
| GSE24585 | Up | 0.0115480498 |
| GSE37065 | Up | 0.1020427832 |
| GSE28863_A1 | Up | 0.4798853331 |
| GSE28863_A2 | Up | 0.6056802894 |
| GSE28863_A3 | Down | -0.4428427833 |
| GSE28863_A4 | Down | -0.2389678510 |
| GSE48662 | Up | 0.0822965024 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027233 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030393 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040920 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 12756294 | These include the induction of the RAB vesicular transport machinery and a general down-regulation of chromatin regulatory molecules |
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