HCSGD entry for MMAB
1. General information
| Official gene symbol | MMAB |
|---|---|
| Entrez ID | 326625 |
| Gene full name | methylmalonic aciduria (cobalamin deficiency) cblB type |
| Other gene symbols | ATR cblB cob |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0008817 | Cob(I)yrinic acid a,c-diamide adenosyltransferase activity | TAS | molecular_function |
| GO:0009235 | Cobalamin metabolic process | TAS | biological_process |
| GO:0009236 | Cobalamin biosynthetic process | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050453 | Cob(II)alamin reductase activity | TAS | molecular_function |
| GO:0055114 | Oxidation-reduction process | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9194820258 | 0.1072310057 | 0.9999902473 | 0.6265254162 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1067965964 |
| GSE13712_SHEAR | Down | -0.2668964190 |
| GSE13712_STATIC | Down | -0.2948775986 |
| GSE19018 | Down | -0.0504022170 |
| GSE19899_A1 | Down | -0.1402331271 |
| GSE19899_A2 | Down | -0.3055041130 |
| PubMed_21979375_A1 | Down | -0.5142463441 |
| PubMed_21979375_A2 | Down | -0.4131864298 |
| GSE35957 | Down | -0.1231592728 |
| GSE36640 | Up | 0.0261303328 |
| GSE54402 | Down | -0.3767724447 |
| GSE9593 | Up | 0.0972031727 |
| GSE43922 | Down | -0.2545522192 |
| GSE24585 | Down | -0.1566508915 |
| GSE37065 | Down | -0.0503814559 |
| GSE28863_A1 | Up | 0.2561829922 |
| GSE28863_A2 | Down | -0.0260313163 |
| GSE28863_A3 | Up | 0.2854344708 |
| GSE28863_A4 | Up | 0.1029706453 |
| GSE48662 | Down | -0.0380696526 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Hydroxocobalamin | DB00200 | APRD01022 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017572 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026432 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046018 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
