HCSGD entry for HPX

1. General information

Official gene symbolHPX
Entrez ID3263
Gene full namehemopexin
Other gene symbolsHX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002639Positive regulation of immunoglobulin productionIEAbiological_process
GO:0002925Positive regulation of humoral immune response mediated by circulating immunoglobulinIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionNAS TAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0006879Cellular iron ion homeostasisTASbiological_process
GO:0015232Heme transporter activityTASmolecular_function
GO:0015886Heme transportTASbiological_process
GO:0016032Viral processIEAbiological_process
GO:0020027Hemoglobin metabolic processIEAbiological_process
GO:0042168Heme metabolic processIEAbiological_process
GO:0042511Positive regulation of tyrosine phosphorylation of Stat1 proteinIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0060335Positive regulation of interferon-gamma-mediated signaling pathwayIEAbiological_process
GO:0071682Endocytic vesicle lumenTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46790403860.95238494740.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0677938945
GSE13712_SHEARUp0.2862243495
GSE13712_STATICUp0.0277211329
GSE19018Up0.0667745954
GSE19899_A1Up0.0231422988
GSE19899_A2Up0.1377816372
PubMed_21979375_A1Up0.2250776738
PubMed_21979375_A2Up0.0872657909
GSE35957Up0.1032032670
GSE36640Up0.0314366057
GSE54402Up0.0809351965
GSE9593Up0.0801548466
GSE43922Up0.0214473926
GSE24585Up0.0591316194
GSE37065Up0.0386184512
GSE28863_A1Down-0.0144311181
GSE28863_A2Down-0.0179087810
GSE28863_A3Up0.2610621316
GSE28863_A4Up0.1094260047
GSE48662Down-0.0128463056

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.